Anti-müllerian hormone is the best predictor of poor response in ICSI cycles of patients with endometriosis.
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Anti-Müllerian hormone (AMH) levels significantly correlated with ovarian response in ICSI cycles and were the best predictor of poor response in patients with endometriosis.
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Abstract
PURPOSE: To correlate ovarian reserve (OR) markers with response in assisted reproduction techniques (ART) and determine their ability to predict poor response among patients with endometriosis (EDT). METHODS: We evaluated ART cycles of 27 women with EDT and 50 with exclusive male factor. Basal follicle stimulating hormone (FSH) and anti-müllerian hormone (AMH) levels were determined. Ovarian response to gonadotropin stimulation was assessed and correlation coefficients calculated between the variables and reserve markers. Areas under the curve (AUC) determined ability of tests to predict poor response. RESULTS: AMH was significantly correlated with response in both groups and it was the only marker with significant discriminative capacity to predict poor response among EDT (AUC = 0.842; 95% CI: 0.651-0.952) and control group (AUC = 0.869; 95% CI: 0.743-0.947). CONCLUSION: Infertile patients with endometriosis can benefit from the pre-therapeutic assessment of OR markers. However, regardless of disease presence, only AMH predicts poor response to stimulus.
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Cited by (3)
- Antimüllerian hormone is reduced in the presence of ovarian endometriomas: a systematic review and meta-analysis 2018
- Evaluation of serum anti-Mullerian hormone levels to assess the ovarian reserve in women with severe endometriosis 2013
- Serum Anti-Müllerian Hormone Levels before Surgery in Patients with Ovarian Endometriomas Compared to Other Benign Ovarian Cysts 2015
Cited by (3)
- Antimüllerian hormone is reduced in the presence of ovarian endometriomas: a systematic review and meta-analysis 2018
- Serum Anti-Müllerian Hormone Levels before Surgery in Patients with Ovarian Endometriomas Compared to Other Benign Ovarian Cysts 2015
- Evaluation of serum anti-Mullerian hormone levels to assess the ovarian reserve in women with severe endometriosis 2013
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