Endometriosis Current Concepts in Pathogenesis and Treatment

A D Noble
Drugs · 1983 · vol. 26(5) , pp. 460–464 · doi:10.2165/00003495-198326050-00005 · PMID:6641541 · W2059894717
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-08 ⓘ

This paper reviews current concepts in endometriosis pathogenesis and treatment, referencing studies on hormonal levels, danazol therapy, progestins, conservative surgery, and medical management.

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This paper is a current-concepts review of endometriosis, covering prevailing ideas on pathogenesis and summarizing medical and surgical treatment approaches reported in the literature. It discusses therapeutic options including danazol, progestins, and conservative surgery, using previously published studies as its evidence base. A major caveat is that, as a narrative review, it does not present new experimental data or a systematic method to assess study quality or compare outcomes across interventions. This paper is centrally about endometriosis — it focuses on current concepts in endometriosis pathogenesis and treatment.

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References Brosens, I.A.; Konickx, P.R. and Corveleyn, P.A.: A study of plasma progesterone, oestradiol — 17β, prolactin and L.H. levels, and of the luteal phase appearance of the ovaries in patients with endometriosis and infertility. British Journal of Obstetrics and Gynaecology 85: 246–250 (1978). Chalmers, J.A.: Danazol in the treatment of endometriosis. Drugs 19: 331–341 (1980). Kistner, R.W.: The use of newer progestins in the treatment of endometriosis. American Journal of Obstetrics and Gynecology 75: 264–278 (1958). Noble, A.D. and Letchworth, A.T.: Treatment of endometriosis: A study of medical management. British Journal of Obstetrics and Gynaecology 8: 726–728 (1980). Sadigh, H.; Naplis, J.D. and Batt, R.E.: Conservative surgery for endometriosis in the infertile couple. Obstetrics and Gynecology 49: 562 (1977). Shervington, P.C.: Medical treatment of endometriosis. Journal of Obstetrics and Gynaecology 3 (Suppl.): S30–S32 (1982). Wheeler, J.M. and Malinek, L.R.: Postoperative danazol therapy in infertile patients with severe endometriosis. Fertility and Sterility 36: 460–463 (1981). Author information Authors and Affiliations Rights and permissions About this article Cite this article Noble, A.D. Endometriosis. Drugs 26, 460–464 (1983). https://doi.org/10.2165/00003495-198326050-00005 Published: Issue date: DOI: https://doi.org/10.2165/00003495-198326050-00005

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis Danazol Danazol Endometriosis Endometriosis Female Humans Pregnancy Pregnancy Complications, Neoplastic Pregnancy Complications, Neoplastic Pseudopregnancy Pseudopregnancy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (7)

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