Recurrence of primary umbilical endometriosis:case report and review of the literature

Danilo Buca; Martina Leombroni; Eleonora Falò; E. Clementini; Mariapia Santomauro; S. Frondaroli; Grazia Camastra; Marco Liberati

Recurrence of primary umbilical endometriosis:case report and review of the literature

Danilo Buca, Martina Leombroni, Eleonora Falò, E. Clementini, Mariapia Santomauro, S. Frondaroli, Grazia Camastra, Marco Liberati

2013 · W1590364508

Case report OA: closed CC0 Metadata only

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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This case report details a recurrent primary umbilical endometriosis in a nulliparous patient and reviews the literature on this uncommon extrapelvic manifestation, emphasizing histopathological diagnosis and surgical excision.

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Abstract

The authors report the case of a 33-year-old nulliparous patient with recurrence of primary spontaneous cutaneous umbilical endometriosis and no history of abdominal or pelvic surgery. The literature describing similar cases is reviewed. Primary endometriosis at extrapelvic sites, and umbilical endometriosis in particular, is very uncommon. The diagnosis is confirmed only by histopathological examination, specifically hematoxylin and eosin staining. Conservative surgical excision with wide margins is the recommended treatment. Adjuvant and neoadjuvant treatment for endometriosis is based on medications which induce endometrial atrophy, such as gonadotropin releasing hormone superactive analogs, or oral estrogen-progestogen formulations given continuously

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Condition tags

endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (15)

Autoimmunity to endometrium and ovary in endometriosis via openalex
CD10 immunohistochemical staining enhances the histological detection of endometriosis via openalex
Cutaneous endometriosis: review of 15 cases diagnosed at a single institution via openalex
Endometriosis of the Umbilicus via openalex
Endometriosis of umbilical cicatrix: case report and review of the literature via openalex
Extragenital endometriosis--a clinicopathological review of a Glasgow hospital experience with case illustrations via openalex
Genetics of endometriosis via openalex
Genetics of endometriosis: current status and prospects via openalex
High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis via openalex
Primary umbilical endometriosis: case report and literature review via openalex
Spontaneous cutaneous umbilical endometriosis: report of a new case with immunohistochemical study and literature review via openalex
Spontaneous endometriosis in an umbilical skin lesion via openalex
Theories on the pathogenesis of endometriosis via openalex
Villar's nodule: a case report and systematic literature review of endometriosis externa of the umbilicus via openalex
W2003193302 via openalex

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License: CC0 · commercial use OK

[1] Autoimmunity to endometrium and ovary in endometriosis via openalex

[2] CD10 immunohistochemical staining enhances the histological detection of endometriosis via openalex

[3] Cutaneous endometriosis: review of 15 cases diagnosed at a single institution via openalex

[4] Endometriosis of the Umbilicus via openalex

[5] Endometriosis of umbilical cicatrix: case report and review of the literature via openalex

[6] Extragenital endometriosis--a clinicopathological review of a Glasgow hospital experience with case illustrations via openalex

[7] Genetics of endometriosis via openalex

[8] Genetics of endometriosis: current status and prospects via openalex

[9] High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis via openalex

[10] Primary umbilical endometriosis: case report and literature review via openalex

[11] Spontaneous cutaneous umbilical endometriosis: report of a new case with immunohistochemical study and literature review via openalex

[12] Spontaneous endometriosis in an umbilical skin lesion via openalex

[13] Theories on the pathogenesis of endometriosis via openalex

[14] Villar's nodule: a case report and systematic literature review of endometriosis externa of the umbilicus via openalex

[15] W2003193302 via openalex