Combination GnRH antagonists for endometriosis: Balancing efficacy with side effects
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⤵ 5 in-corpus citations
Abstract
Endometriosis is a chronic pain condition affecting 1 in 10 women. There is an unmet need for better medical treatments for endometriosis. We spotlight trials of a single preparation combined HRT-GnRH antagonist (Relugolix) by Giudice et al.,1 for endometriosis-associated pain.
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References (10)
- O-132 Sustained efficacy and safety of relugolix combination therapy in women with endometriosis-associated pain: SPIRIT 52-week data via openalex
- Once daily oral relugolix combination therapy versus placebo in patients with endometriosis-associated pain: two replicate phase 3, randomised, double-blind, studies (SPIRIT 1 and 2) via openalex
- SnapShot: Endometriosis via openalex
- Top ten endometriosis research priorities in the UK and Ireland via openalex
- Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist via openalex
- Two-year efficacy and safety of relugolix combination therapy in women with endometriosis-associated pain: SPIRIT open-label extension study via openalex
- W4214754424 via openalex
- W3165294846 via openalex
- W3013010875 via openalex
- W2132577372 via openalex
Cited by (5)
- Investigational drugs for the treatment of dysmenorrhea 2024
- Is high-intensity focused ultrasound a magical solution to endometriosis? A systematic review 2024
- Efficacy and Safety of Oral Gonadotropin-Releasing Hormone Antagonist, Relugolix, in Endometriosis: A Meta-Analysis of Randomized Clinical Trials 2024
- Transforming Endometriosis Management: Insights from a Six-Year Application of the 4P Approach 2024
- Update on the management of endometriosis-associated pain in France 2023
Source provenance
- europepmc
- last seen: 2026-06-11T06:19:48.454388+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-06-11T06:19:26.824110+00:00
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