Reply to: Continuous or cyclic contraceptives for endometriosis: a question still without an answer

Konstantinos A Zorbas, Konstantinos P Economopoulos, Nikolaos Vlahos, Nikos F Vlahos
Archives of gynecology and obstetrics · 2015 · vol. 292(3) , pp. 483–484 · doi:10.1007/s00404-015-3781-3 · PMID:26054826 · W610201088
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-12 ⓘ

This reply to a previous comment discusses the ongoing debate regarding the effectiveness of continuous versus cyclic oral contraceptives for endometriosis management.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-12 · read from full text ⓘ

This paper is a short reply to a prior comment about the evidence comparing continuous versus cyclic contraceptive regimens for endometriosis. It frames the discussion in relation to earlier publications and systematic-review findings, referencing studies that have compared continuous and cyclic oral contraceptives in endometriosis-associated symptoms and outcomes. The authors do not present new original data in this reply, and the limitation is that it primarily addresses debate and interpretation rather than generating additional trial results. This paper is centrally about endometriosis — it directly responds to the comment “Continuous or cyclic contraceptives for endometriosis,” focusing on the ongoing uncertainty in comparing continuous versus cyclic contraceptive approaches for endometriosis.

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References Troncon JK, Neto OB, Nogueira AA, Rosa e Silva JC (2015) Continuous or cyclic contraceptives for endometriosis: a question still without an answer. Arch Gynecol Obstet. doi:10.1007/s00404-015-3778-y Zorbas K, Economopoulos KP, Vlahos N (2015) Continuous versus cyclic oral contraceptives for the treatment of endometriosis: a systematic review. Arch Gynecol Obstet. doi:10.1007/s00404-015-3641-1 (Epub ahead of print) Vercellini P, Frontino G, De Giorgi O, Pietropaolo G, Pasin R, Crosignani PG (2003) Continuous use of an oral contraceptive for endometriosis-associated recurrent dysmenorrhea that does not respond to a cyclic pill regimen. Fertil Steril 80(3):560–563 Seracchioli R, Mabrouk M, Frasca C, Manuzzi L, Montanari G, Keramyda A, Venturoli S (2010) Long-term cyclic and continuous oral contraceptive therapy and endometrioma recurrence: a randomized controlled trial. Fertil Steril 93(1):52–56 Seracchioli R, Mabrouk M, Frasca C, Manuzzi L, Savelli L, Venturoli S (2010) Long-term oral contraceptive pills and postoperative pain management after laparoscopic excision of ovarian endometrioma: a randomized controlled trial. Fertil Steril 94(2):464–471 Vlahos N, Vlachos A, Triantafyllidou O, Vitoratos N, Creatsas G (2013) Continuous versus cyclic use of oral contraceptives after surgery for symptomatic endometriosis: a prospective cohort study. Fertil Steril 100(5):1337–1342 Conflict of interest None. Author information Authors and Affiliations Corresponding author Additional information This reply refers to the comment available at doi:10.1007/s00404-015-3778-y. Rights and permissions About this article Cite this article Zorbas, K.A., Economopoulos, K.P. & Vlahos, N.F. Reply to: Continuous or cyclic contraceptives for endometriosis: a question still without an answer. Arch Gynecol Obstet 292, 483–484 (2015). https://doi.org/10.1007/s00404-015-3781-3 Published: Issue date: DOI: https://doi.org/10.1007/s00404-015-3781-3

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Condition tags

endometriosis

MeSH descriptors

Contraceptive Agents Endometriosis Contraceptive Agents Endometriosis Female Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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