ENDOMETRIOSE PROFUNDA: O DESAFIO DO DIAGNÓSTICO TARDIO E SEUS IMPACTOS NA SAUDE DA MULHER

MILENA NUNES CHAVES DA FÉ DE JESUS, Yasmin Fernandes Queiroz, MARIA BEATRIZ PEREIRA DA SILVA, Anna Júlia Araújo Cortez, Maria Eduarda Carvalho Távora, Ricardo Ramsés Guedes Ribeiro, Ana Carolina de Sousa Dourado, Sarah Victoria Gomes da Silva, Maria Vitória Painim Infeld, Daniely Domingos Moreira, Jhuly Stefany Ribeiro dos Santos, Julliana Gonçalves de Araújo, João Gabriel Barbosa Buhatem Matos, Cézar Rodrigues de Deus Filho
In: Asclepius International Journal of Scientific Health Science · 2026 · vol. 5(3) , pp. 01–07 · doi:10.70779/aijshs.v5i3.513 · W7133205342
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This integrative review found that deep infiltrating endometriosis diagnosis averages 7-10 years due to pain normalization and lack of primary care screening, necessitating advanced imaging and earlier detection for fertility and quality of life.

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This paper is an integrative literature review that examines deep infiltrative endometriosis, defined as endometrial tissue infiltrating the peritoneum beyond 5 mm, using studies identified in PubMed, SciELO, and LILACS from 2020 to 2025. It reports that the time to definitive diagnosis remains about 7 to 10 years on average, shaped by normalization of menstrual pain and limited screening in primary care. The paper emphasizes that lesion mapping relies on ultrasound with bowel preparation and magnetic resonance imaging, aiming to avoid diagnostic delays leading to higher-morbidity surgical interventions, while explicitly noting the review’s focus on literature rather than direct new clinical data. This paper is centrally about endometriosis — it focuses specifically on deep infiltrative (deep) endometriosis, delayed diagnosis, and impacts on women’s health.

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Abstract

A endometriose profunda infiltrativa representa um dos quadros mais severos da ginecologia, caracterizando-se pela presença de tecido endometrial em profundidade superior a cinco milímetros no peritônio. O presente estudo consistiu em uma revisão integrativa da literatura baseada em dados do PubMed, SciELO e LILACS, abrangendo o período de 2020 a 2025. Os resultados demonstram que o intervalo para o diagnóstico definitivo ainda atinge uma média de sete a dez anos, sendo influenciado pela normalização da dor menstrual e pela carência de triagem eficaz na atenção primária. A discussão destaca que a utilização da ultrassonografia com preparo intestinal e da ressonância magnética é crucial para o mapeamento das lesões, evitando que o atraso diagnóstico resulte em intervenções cirúrgicas de alta morbidade. Conclui-se que a antecipação diagnóstica é fundamental para preservar a qualidade de vida e a fertilidade feminina, sendo necessária a capacitação profissional e a democratização do acesso a exames especializados.
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DEEP ENDOMETRIOSIS: THE CHALLENGE OF LATE DIAGNOSIS AND ITS IMPACT ON WOMEN’S HEALTH DOI: https://doi.org/10.70779/aijshs.v5i3.513Palavras-chave: Deep endometriosis; Delayed diagnosis; Women's health; Image mapping; Pelvic pain.Resumo Deep infiltrative endometriosis represents one of the most severe gynecological conditions, characterized by the presence of endometrial tissue at a depth exceeding five millimeters in the peritoneum. The present study consisted of an integrative literature review based on data from PubMed, SciELO, and LILACS, covering the period from 2020 to 2025. The results demonstrate that the interval for definitive diagnosis still averages seven to ten years, influenced by the normalization of menstrual pain and the lack of effective screening in primary care. The discussion highlights that the use of ultrasound with bowel preparation and magnetic resonance imaging is crucial for lesion mapping, preventing diagnostic delays from resulting in high-morbidity surgical interventions. It is concluded that early diagnosis is fundamental to preserving women's quality of life and fertility, requiring professional training and the democratization of access to specialized examinations. Referências ABRÃO, Maurício S. et al. Deep Endometriosis: A Surgical and Diagnostic Challenge. Journal of Minimally Invasive Gynecology, v. 28, n. 3, p. 507-514, 2021. DOI: 10.1016/j.jmig.2020.12.005. BECKER, Christian M. et al. ESHRE guideline: endometriosis. Human Reproduction Open, v. 2022, n. 2, hoac009, 2022. DOI: 10.1093/hropen/hoac009. CHAPRON, Charles et al. Endometriosis: a profound impact on women's lives. The Lancet, v. 400, n. 10352, p. 11-13, 2022. DOI: 10.1016/S0140-6736(22)01540-X. FEBRASGO. Protocolos de Ginecologia: Endometriose. São Paulo: Elsevier, 2023. TAYLOR, Hugh S. et al. Endometriosis is a systemic disease, not only a disease of the reproductive system. The Lancet, v. 397, n. 10276, p. 839-855, 2021. DOI: 10.1016/S0140-6736(21)00389-5. ZANNONI, Letizia et al. Ultrasound mapping for deep endometriosis: the importance of a standardized reporting system. Ultrasound in Obstetrics & Gynecology, v. 63, n. 1, p. 98-106, 2024. DOI: 10.1002/uog.26250. Downloads Publicado Como Citar Edição Seção Licença Copyright (c) 2026 Asclepius International Journal of Scientific Health Science Este trabalho está licenciado sob uma licença Creative Commons Attribution-NonCommercial 4.0 International License. It is also licensed under a LOCKSS (Lots of Copies Keep Stuff Safe) sistem.

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