[Evaluation of the generation of interleukin-10 by peripheral blood lymphocytes in women with endometriosis].

K Szyłło, Szyłło K, Krzysztof Szyłło, Lewy J, Jarosław Lewy, J Lewy, Tchórzewski H, H Tchórzewski, Głowacka E, Ewa Głowacka, E Głowacka, M Banasik, Banasik M, Mirosław Banasik, P Lewkowicz, Przemysław Lewkowicz, Kamer-Bartosińska A, Anna Kamer-Bartosińska, A Kamer-Bartosińska
Ginekologia polska · 2001 · vol. 72(5) , pp. 437–41 · PMID:11526790 · W2432853519
article OA: closed CC0 ⤵ 1 in-corpus citation
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Peripheral blood lymphocytes from women with endometriosis generated less interleukin-10 compared to healthy controls, a finding potentially linked to immune dysfunction and disease progression.

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Abstract

The aim of study was the evaluation of generating the IL-10 by peripheral blood lymphocytes in women with endometriosis according to the stage of of the disease. Cytokine was estimated by immunoenzymatic method Elisa. The generation of IL-10 by peripheral blood lymphocytes was lower in patients with all stages of endometriosis than in control group. Decreased IL-10 generating observed in our study was not statistically significant, but it may correlate with disorders of immunological cell response. It may also play a role in a development and progression of endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Interleukin-10 Lymphocytes Pelvic Inflammatory Disease Adult Cell Count Cell Count Endometriosis Endometriosis Endometriosis Female Humans Interleukin-10 Laparoscopy Laparoscopy Lymphocytes Pelvic Inflammatory Disease Pelvic Inflammatory Disease Severity of Illness Index

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