Pelvic Inflammatory Disease: An Evidence-Based Guideline

Irami Araújo-Filho
In: Interventions in Gynaecology and Women’s Healthcare · 2018 · vol. 1(4) · doi:10.32474/igwhc.2018.01.000120 · W2903214952
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This evidence-based guideline, adapted to Brazilian primary care, provides recommendations for treating pelvic inflammatory disease, particularly in young, underserved women.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This evidence-based guideline, developed from a literature review (PUBMED, SCOPUS, Web of Science, and EMBASE) and recent randomized trials, systematic reviews, meta-analyses, and guidelines, addresses diagnosis and management of pelvic inflammatory disease (PID) in women—particularly in the context of Brazilian primary care and limited access to information. It describes PID as an acute upper genital tract infection (uterus, ovaries, fallopian tubes) typically initiated by a sexually transmitted agent, noting polymicrobial involvement beyond Chlamydia trachomatis and Neisseria gonorrhoeae, including roles for bacterial vaginosis and Mycoplasma genitalium, and emphasizes empiric broad antibiotic coverage with ceftriaxone due to gonococcal resistance. The guideline highlights diagnostic uncertainty, stating clinical diagnosis is imprecise and that laparoscopy can confirm in selected scenarios but is not sensitive enough for a gold standard, with a caveat that endometrial biopsy is not recommended unless part of a protocol. Relevance to endometriosis and/or adenomyosis: the paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

A group of medical students and researchers from the Northeastern Region of Brazil produced this guideline, in order to provide doctors or health teams who work in the so-called Brazilian Primary Care Programs as well as those professionals working in the most remote interiors of the country.Guideline-based on current scientific evidence and adapted to the Brazilian reality, to help in the treatment and recovery of the health of women affected by the pelvic inflammatory disease, especially those young, adolescent patients with no access to information.

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