Post-Caesarean Huge Isthmocele with Multiple Endometriomas and Cervical Stenosis: Laparoscopic Excision and Repair

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This study reports a laparoscopic excision and repair of a huge post-cesarean isthmocele with multiple endometriomas and cervical stenosis in a 30-year-old woman presenting with infertility and pain.

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Abstract

BACKGROUND: Cesarean scar defects or isthmoceles are increasingly detected in the recent times due to the rise in cesarean rates worldwide. They may develop due to poor healing at myometrial site. The pouch accumulates the menstrual blood and very rarely in long standing cases develops endometriomas in the wall. CASE PRESENTATION: A 30-year-old woman, para 1 living 1 with previous cesarean delivery 9 years back, presented to us with secondary infertility, chronic pelvic pain and post menstrual bleeding. A routine Transvaginal ultrasonography (TVS) showed a large fluid filled outpouching adjoining the uterine scar line, in communication with endometrial cavity. T2 weighted magnetic resonance Imaging (MRI) showed a huge isthmocele arising from the scar defect at lower uterine segment measuring 96 x 60 x52 mm with multiple endometrial rests in the wall showing shading and hypo intensity. The ishtmocele was laparoscopically excised and defect closed in two layers with hysteroscopic transillumination guidance. On hisptopathlogical examination, the lining of isthmocele had endocervical epithelium with thick fibromuscular tissue and focal areas of endometriosis. Postoperative period was uneventful and patient was discharged on third postoperative day. The patient was relieved of her pain abdomen and postmenstrual bleeding at 6 months follow-up. CONCLUSION: Laparoscopic approach is the preferred surgical technique in huge isthmoceles. Endometrioma develop within the wall of the pseudosac during natural course of the disease in longstanding ishthmoceles. Meticulous closure of uterine incision during cesarean section making sure that edges are taken properly into the stiches along with proper antibiotic coverage in cases with premature rupture of membranes (PROM) can prevent occurrence of isthmocele. Early diagnosis and surgical repair can prevent the progressive disease and Cesarean scar defect Syndrome.
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Abstract

Background Cesarean scar defects or isthmoceles are increasingly detected in the recent times due to the rise in cesarean rates worldwide. They may develop due to poor healing at myometrial site. The pouch accumulates the menstrual blood and very rarely in long standing cases develops endometriomas in the wall. Case presentation A 30-year-old woman, para 1 living 1 with previous cesarean delivery 9 years back, presented to us with secondary infertility, chronic pelvic pain and post menstrual bleeding. A routine Transvaginal ultrasonography (TVS) showed a large fluid filled outpouching adjoining the uterine scar line, in communication with endometrial cavity. T2 weighted magnetic resonance Imaging (MRI) showed a huge isthmocele arising from the scar defect at lower uterine segment measuring 96 x 60 x52 mm with multiple endometrial rests in the wall showing shading and hypo intensity. The ishtmocele was laparoscopically excised and defect closed in two layers with hysteroscopic transillumination guidance. On hisptopathlogical examination, the lining of isthmocele had endocervical epithelium with thick fibromuscular tissue and focal areas of endometriosis. Postoperative period was uneventful and patient was discharged on third postoperative day. The patient was relieved of her pain abdomen and postmenstrual bleeding at 6 months follow-up.

Conclusion

Laparoscopic approach is the preferred surgical technique in huge isthmoceles. Endometrioma develop within the wall of the pseudosac during natural course of the disease in longstanding ishthmoceles. Meticulous closure of uterine incision during cesarean section making sure that edges are taken properly into the stiches along with proper antibiotic coverage in cases with premature rupture of membranes (PROM) can prevent occurrence of isthmocele. Early diagnosis and surgical repair can prevent the progressive disease and Cesarean scar defect Syndrome. Abbreviations - CSS: - Caesarean scar syndrome - TVS: - Transvaginal ultrasonography - MRI: - Magnetic resonance imaging - PROM: - Premature rupture of membranes - SHG: - Sonohysterography - RM: - Residual myometrium

References

Naji O, Abdallah Y, Bij De Vaate AJ, Smith A, Pexsters A, Stalder C, McIndoe A, Ghaem-Maghami S, Lees C, Brolmann HA, Huirne JA, Timmerman D, Bourne T. Standardized approach for imaging and measuring Cesarean section scars using ultrasonography. Ultrasound Obstet Gynecol. 2012;39:252–9. https://doi.org/10.1002/uog.10077. Rupa1 R, Suchana Kushvaha1, Venkatesh K. Uterine isthmocele—A frequently overlooked complication of cesarean sections. Indian J Radiol Imaging 31(3/2021©2021) Vervoort A, Vissers J, Hehenkamp W, Brölmann H, Huirne J. The effect of laparoscopic resection of large niches in the uterine caesarean scar on symptoms, ultrasound findings and quality of life: a prospective cohort study. BJOG. 2018;125(3):317–25. Stavros Karampelas, Georges Salem Wehbe, Laurent de Landsheere, Dominique A. Badr, Linda Tebache and Michelle Nisolle. Laparoscopic isthmocele repair: efficacy and benefits before and after subsequent cesarean section. J Clin Med. 2021;10, 5785. https://doi.org/10.3390/jcm10245785 Funding There were no funds or grants involved. Author information Authors and Affiliations Contributions All authors contributed to the patient management and follow-up. Corresponding author Ethics declarations Conflict of interest None of the authors have any potential conflict of interest. Ethical Statement Informed consent was obtained from the patient for presenting her data for publication. All parts of Declaration of Helsinki have been applied. Informed Consent The patient involved in this was appropriately consented for this publication using institution’s policy for publication. Additional information Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Akkamahadevi C. Hiremath, MBBS, M.D. (Obstetrics & Gynaecology) is a Senior Consultant and Head of the Department of Obstetrics & Gynaecology; Anuja Doolam, MBBS, DNB (Obstetrics & Gynaecology) is a Junior Consultant; K. S. Shivakumar, MBBS, MS, MCh (Urology) is a Senior Consultant; Dimpi Sinha, MBBS, M.D.(Radiology) is a Senior Consultant; N. S. Nayana, MBBS, M.D.(OncoPathology) is a Fellow; Geetanjali Tulapurkar, MBBS, M.D. (Anaesthesiology) is Senior Consultant. Rights and permissions About this article Cite this article Hiremath, A.C., Doolam, A., Shivakumar, K.S. et al. Post-Caesarean Huge Isthmocele with Multiple Endometriomas and Cervical Stenosis: Laparoscopic Excision and Repair. J Obstet Gynecol India 75, 75–78 (2025). https://doi.org/10.1007/s13224-023-01877-2 Received: Accepted: Published: Version of record: Issue date: DOI: https://doi.org/10.1007/s13224-023-01877-2

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