Herlyn-Werner-Wunderlich syndrome: A rare cause of pain in the left iliac fossa
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This paper describes the radiological characteristics of Herlyn-Werner-Wunderlich syndrome, a rare Müllerian duct anomaly causing uterus didelphys with potential complications like pain and endometriosis.
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Abstract
Alterations of the Müllerian ducts are rare but often treatable causes of infertility. Uterus didelphys is caused by a complete or almost complete lack of fusion of the Müllerian ducts during embryological development. As a result, two separate symmetrical uterine cavities develop with two cervices and no communication between these cavities; this is often associated with a vaginal septum, which can have a transverse wall that blocks one of the hemivaginas. Symptoms begin to develop in menarche, and complications related to a retrograde menstrual flow arise, along with pelvic adhesions and endometriosis. Some kidney abnormalities may occur. Magnetic resonance imaging can be used to diagnose and distinguish surgically correctable forms of Müllerian duct alterations. The surgical approach depends on the imaging findings. The objective of this article is to describe the radiological characteristics of the Herlyn-Werner-Wunderlich syndrome.
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- Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome with a single uterus via openalex
- W192717539 via openalex
- W1989852475 via openalex
- W2019652977 via openalex
- W2049668383 via openalex
- W2130898441 via openalex
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- last seen: 2026-06-04T00:00:01.174412+00:00
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- last seen: 2026-09-04T06:34:25.427880+00:00
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