Florid Polypoid Endometriosis Exacerbated by Tamoxifen Therapy in Breast Cancer
article
OA: closed
CC0
⤵ 4 in-corpus citations
AI-generated summary
This case describes a premenopausal woman whose tamoxifen therapy for breast cancer coincided with and potentially exacerbated florid polypoid endometriosis.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
BACKGROUND We report an unusual case where tamoxifen may have exacerbated the growth of multiple polypoid endometriotic implants. CASE A premenopausal woman with right breast intraductal carcinoma underwent modified radical mastectomy and received six courses of chemotherapy, followed by continuous oral tamoxifen. Irregular vaginal bleeding was noted 5 years after the mastectomy and transvaginal ultrasound detected a 6-cm cul-de-sac mass. The serum CA 125 level was 138.86 U/mL. Surgical pathology showed florid polypoid endometriosis over the resected rectal segment and endometriotic implants over multiple biopsy sites of the peritoneal surface. CONCLUSION The estrogenic effects of tamoxifen may have induced florid endometriosis in this hypoestrogenic woman. If breast cancer patients have preexisting endometriosis, adjuvant hormonal therapy other than tamoxifen should be considered.
My notes (saved in your browser only)
Condition tags
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (7)
- Adenomyosis in Postmenopausal Breast Cancer Patients Treated with Tamoxifen: A New Entity? via openalex
- Medical management of endometriosis and infertility via openalex
- Role of cytokines in endometriosis via openalex
- Tamoxifen treatment and gynecologic side effects: a review via openalex
- Treating endometriosis as an autoimmune disease via openalex
- W1974993766 via openalex
- W2134551047 via openalex
Cited by (4)
- Atypical endometriosis: a review of an incompletely understood putative precursor of endometriosis-associated ovarian carcinoma 2023
- A case of polypoid endometriosis mimicking advanced ovarian carcinoma with rapid growth, invasion, and dissemination 2022
- Polypoid endometriosis in a young woman: a case report and review of literature 2019
- Polypoid Endometriosis of the Cervix Mimicking a Uterine Malformation: Case Report 2013
Source provenance
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- unpaywall
- last seen: 2026-06-02T02:00:03.124865+00:00
License: CC0
· commercial use OK