Searching the connection between endometriosis and abortion

conferenceseries.com Volume: 00Gynecology & Obstetrics Page 6 Reproduction Fertility 2021 July 21, 2021 | Webinar July 21, 2021 | Webinar 3rd International Conference on Womens HealtH , RepR oduction and FeRtility Bárbara Laranjeiro et al., Gynecol Obstet (Sunnyvale) 2021, ISSN: 2161-0932 Searching the connection between endometriosis and abortion Bárbara Laranjeiro1, Mariana Robalo Cordeiro2, Ana Luísa Areia1,3, Margarida FigueiredoDias 2,4 1Obstetric Department, Universitary Hospital Center of Coimbra, Portugal. 2Gynecology Department, Universitary Hospital Center of Coimbra, Portugal. 3Faculty of Medicine, University of Coimbra, Coimbra, Portugal. 4Universitary Clinic of Gynecology, Faculty of Medicine, University of Coimbra, Portugal It is known that both structural changes in the abdominal cavity caused by the presence of endometrial tissue outside the uterus and chronic inflammation compromise pregnancy outcomes in patients with endometriosis. Indeed, the existence of an increased risk of abortion in patients with endometriosis has been reported. However, considering the variety of clinical presentations, as well as the controversies that exists regarding the pathophysiology and the best methodology to be used to study these patients, consensus has not yet been reached. This work aims to evaluate the incidence of abortion in patients with previous histological diagnosis of endometriosis and to explore a possible association with the extent and the location of endometriosis. Based on clinical records, patients with a histological diagnosis of endometriosis were studied (N = 190) and 40 patients referred previous abortion (21%). In this subgroup, there was a higher incidence of mixed endometriosis (localized both in ovarium and peritoneum) and disease stage III-IV (N = 25 and N = 32, respectively), not significantly different (p> 0.005) from patients without this background. Regarding symptoms, 50% (20/40) of them were symptomatic. The most frequent symptoms were dysmenorrhea (28/40) and pelvic pain (26/40). As so, based on this study, we can infer that there is no significant association between the phenotype of endometriosis (location, stage, symptoms) in patients with previous abortion when compared to women with term pregnancy. Further research should be conducted to clarify the link between endometriosis clinical features and obstetric outcomes. Biography Bárbara Laranjeiro is a first year Resident of Gynecology and Obstetrics from Coimbra, Portugal. She finished her Master Degree in Medicine from the Faculty of Medicine of University of Coimbra with 23 years, in 2019. Started her career as Resident in 2020, completing one year of General Formation, and starting as Resident of Gynecology and Obstetrics in 2021, in Coimbra Hospital and Universitary Centre (CHUC), the biggest Portuguese hospital center, working till the present moment in the Obstetric Department [email protected]