{"paper_id":"3a48b6b9-ea0d-448d-8fb4-d7183bc4a750","body_text":"conferenceseries.com\nVolume: 00Gynecology & Obstetrics\nPage 6\nReproduction Fertility 2021\nJuly 21, 2021 | Webinar\nJuly 21, 2021 | Webinar\n3rd International Conference on Womens  HealtH , RepR oduction  and  FeRtility\nBárbara Laranjeiro et al., Gynecol Obstet (Sunnyvale) 2021, ISSN: 2161-0932\nSearching the connection between endometriosis and abortion\nBárbara Laranjeiro1, Mariana Robalo Cordeiro2, Ana Luísa Areia1,3, Margarida FigueiredoDias 2,4\n1Obstetric Department, Universitary Hospital Center of Coimbra, Portugal.\n2Gynecology Department, Universitary Hospital Center of Coimbra, Portugal.\n3Faculty of Medicine, University of Coimbra, Coimbra, Portugal.\n4Universitary Clinic of Gynecology, Faculty of Medicine, University of Coimbra, Portugal\nIt is known that both structural changes in the abdominal cavity caused by the presence of endometrial tissue outside the uterus and chronic inflammation \ncompromise pregnancy outcomes in patients with endometriosis. Indeed, the existence of an increased risk of abortion in patients with endometriosis has been \nreported. However, considering the variety of clinical presentations, as well as the controversies that exists regarding the pathophysiology and the best methodology \nto be used to study these patients, consensus has not yet been reached. This work aims to evaluate the incidence of abortion in patients with previous histological \ndiagnosis of endometriosis and to explore a possible association with the extent and the location of endometriosis. Based on clinical records, patients with a \nhistological diagnosis of endometriosis were studied (N = 190) and 40 patients referred previous abortion (21%). In this subgroup, there was a higher incidence \nof mixed endometriosis (localized both in ovarium and peritoneum) and disease stage III-IV (N = 25 and N = 32, respectively), not significantly different (p> 0.005) \nfrom patients without this background. Regarding symptoms, 50% (20/40) of them were symptomatic. The most frequent symptoms were dysmenorrhea (28/40) \nand pelvic pain (26/40). As so, based on this study, we can infer that there is no significant association between the phenotype of endometriosis (location, stage, \nsymptoms) in patients with previous abortion when compared to women with term pregnancy. Further research should be conducted to clarify the link between \nendometriosis clinical features and obstetric outcomes.\nBiography\nBárbara Laranjeiro is a first year Resident of Gynecology and Obstetrics from Coimbra, Portugal. She finished her Master Degree in Medicine from the Faculty \nof Medicine of University of Coimbra with 23 years, in 2019. Started her career as Resident in 2020, completing one year of General Formation, and starting as \nResident of Gynecology and Obstetrics in 2021, in Coimbra Hospital and Universitary Centre (CHUC), the biggest Portuguese hospital center, working till the \npresent moment in the Obstetric Department                                                                                                           \nbarbaralaranjeiro@gmail.com","source_license":"CC0","license_restricted":false}