Синдром поликистозных яичников и дефицит витамина D

The XXI century has become the century of ecological and, consequently, reproductive ill health, as any unfavorable factors of the environment negatively influence hormonal homeostasis. The increase in the number of infertile couples and the growing need for ART - the realities of the modern world, and the effectiveness of IVF has not increased. In the structure of the causes of infertility, the palm of the championship is now endocrine, and in the structure of the causes of female infertility of about 20-40%, infertility is associated with the lack of ovulation. The cause of 75% of all anovulatory disorders is polycystic ovary syndrome (PCOS). However, the pathogenesis of anovulation and methods for its effective overcoming in PCOS are still not fully understood, which causes numerous versions and contraversies in the therapy of this disease, reflected in this literature review. According to the findings of modern research, PCOS is very often combined with a vita min D deficiency (67-85% of women with PCOS have a varying degree of vitamin D deficiency) [1]. This article considers both the pathogenesis of PCOS and the low level of vitamin D in PCOS, with a violation of the reproductive function, a review of the world studies on the efficacy of PCOS therapy with vitamin D, the feasibility of its inclusion in the algorithm for the treatment of anovulatory infertility, which will expand the presentation on the pathogenesis of the development of anovulation in PCOS, to increase the effectiveness of overcoming infertility associated with anovulation in PCOS.