GnRH analogs versus expectant management in minimal and mild endometriosis-associated infertility.

R Marana, Riccardo Marana, FRANCESCO V. PAIELLI, F V Paielli, Ludovico Muzii, L Muzii, S Dell'Acqua, S Mancuso, Stefano Mancuso
Acta Europaea fertilitatis · 1995 · vol. 25(1) , pp. 37–41 · PMID:7887079 · W2640867
article OA: closed CC0 ⤵ 8 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This study found comparable pregnancy rates between GnRH analog treatment and expectant management in infertile patients with minimal and mild endometriosis, suggesting expectant management is more cost-effective.

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Abstract

The aim of the present study is to compare the outcome of GnRH analog treatment versus expectant management in infertile patients with minimal and mild endometriosis. From January 1987 to December 1990, 14 patients with stage I and II endometriosis underwent a six-month course of the GnRH analog buserelin, whereas 38 patients underwent expectant management. The two groups were comparable as to mean age of the patients, mean length of infertility prior to diagnosis and mean scores of endometriosis. No major tubal or male factor of infertility was present in any patient. Cumulative pregnancy rates at 12 months were comparable in the two groups (48% for GnRH analog treatment and 42% for expectant management). Expectant management should therefore be considered the most cost-effective option in the management of mild endometriosis-associated infertility.

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Condition tags

endometriosisinfertility

MeSH descriptors

Buserelin Endometriosis Infertility Buserelin Buserelin Endometriosis Female Humans Infertility Infertility Pregnancy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (8)

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License: CC0 · commercial use OK