The effect of endometrioma on ovarian reserve

Małgorzata Szczepańska, Paweł P. Jagodzińśki, Ewa Wender-Ożegowska
In: Journal of Medical Science · 2017 · vol. 86(3) , pp. 237–239 · doi:10.20883/jms.2017.201 · W2765193496
article OA: diamond CC0
🔓 Open OA copy Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

Ovarian endometriomas negatively impact ovarian reserve markers like AMH and AFC, and IVF outcomes, necessitating careful consideration for surgical intervention in women of reproductive age, particularly those not yet having children.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-13 · read from full text ⓘ

This paper is a review of the evidence on how ovarian endometriomas affect ovarian reserve, focusing on ovarian reserve markers such as anti-Müllerian hormone (AMH), antral follicle count (AFC), and IVF outcomes. Across the cited studies, the authors report that endometriomas can be associated with negative changes in these markers, though the review highlights that the clinical and research implications may depend on how cases are managed, including surgical timing and approach. A major caveat emphasized is that treatment decisions—particularly surgery for endometrial cysts—should be considered carefully, especially for women who have not yet had childbirth. This paper is centrally about endometriosis — it specifically reviews how ovarian endometriomas impact ovarian reserve markers like AMH and AFC.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

An ovarian endometrioma is a very common form of endometriosis in women of reproductive age. This review presents the current state of research on ovarian reserve in women with ovarian endometriomas. Endometrioma can negatively affect ovarian markers: the anti-Müllerian hormone (AMH), antral follicle count (AFC) and in vitro fertilisation (IVF) results. Decisions on the surgical treatment of endometrial cysts should be carefully thought through, especially in women who have not given birth.
Full text 4,585 characters · extracted from oa-doi-fallback · click to expand
The effect of endometrioma on ovarian reserve DOI: https://doi.org/10.20883/jms.2017.201Keywords: endometriosis, AMH, ovarian reserveAbstract An ovarian endometrioma is a very common form of endometriosis in women of reproductive age. This review presents the current state of research on ovarian reserve in women with ovarian endometriomas. Endometrioma can negatively affect ovarian markers: the anti-Müllerian hormone (AMH), antral follicle count (AFC) and in vitro fertilisation (IVF) results. Decisions on the surgical treatment of endometrial cysts should be carefully thought through, especially in women who have not given birth.Downloads References Redwine DB. Ovarian endometriosis: a marker for more extensive pelvic and intestinal disease. Fertil Steril. 1999;72:310–315. Jenkins S, Olive DL, Haney AF. Endometriosis: pathogenetic implications of the anatomic distribution. Obstet Gynecol. 1986;67:335–338. Vercellini P, Frontino G, De Giorgi O, Aimi G, Zaina B, Crosignani PG. Comparison of a levonorgestrel-releasing intrauterine device versus expectant management after conservative surgery for symptomatic endometriosis: a pilot study. Fertil Steril. 2003;80:305–309. Garcia-Velasco JA, Arici A. Is the endometrium or oocyte/embryo affected in endometriosis? Hum Reprod. 1999 Dec;14(Suppl. 2):77–89. Garrido N, Navarro J, García-Velasco J, Remoh J, Pellice A, Simón C.The endometrium versus embryonic quality in endometriosis-related infertility. Hum Reprod Update. 2002;Jan-Feb;8(1):95–103. Sanchez AM, Vigano P, Somigliana E, Panina-Bordignon P, Vercellini P, Candiani M. The distinguishing cellular and molecular features of the endometriotic ovarian cyst: from pathophysiology to the potential endometrioma-mediated damage to the ovary. Hum Reprod Update. 2013;20(2):217–230. Benaglia L, Somigliana E, Vercellini P, Abbiati A, Ragni G, Fedele L. Endometriotic ovarian cysts negatively affect the rate of spontaneous ovulation. Hum Reprod. 2009 Sep;24(9):2183–6. Hughesdon PE. The structure of endometrial cyst of the ovary. J Obstet Gynaecol Br Emp. 1957 Aug;64(4):481–7. Hachisuga T, Kawarabayashi T. Histopathological analysis of laparoscopically treated ovarian endometriotic cysts with special reference to loss of follicles. Hum Reprod. 2002;17:432–435. Hwu YM, Wu FS, Li SH, Sun FJ, Lin MH, Lee RK. The impact of endometrioma and laparoscopic cystectomy on serum anti-Müllerian hormone levels. Reprod Biol Endocrinol. 2011 Jun 9;9:80. Goodman LR, Goldberg JM, Flyckt RL, Gupta M, Harwalker J, Falcone T. Effect of surgery on ovarian reserve in women with endometriomas, endometriosis and controls. Am J Obstet Gynecol. 2016 Nov;215(5):589.e1–589.e6. Ding Y, Yuan Y, Ding J, Chen Y, Zhang X, Hua K. Comprehensive Assessment of the impact of laparoscopic ovarian cystectomy on ovarian reserve. J Minim Invasive Gynecol. 2015;22(7):1252–9. La Marca A, Sunkara SK. Individualization of controlled ovarian stimulation in IVF using ovarian reserve markers: From theory to practice. Hum Reprod Update. 2013;20(1):124–40. Iwase A, Hirokawa W, Goto M, Takikawa S, Nagatomo Y, Nakahara T, Manabe S, Kikkawa F.Serum anti-Müllerian hormone level is a useful marker for evaluating the impact of laparoscopic cystectomy on ovarian reserve.Fertil Steril. 2010Dec;94(7):2846–9. Horikawa T, Nakagawa K, Ohgi S, Kojima R, Nakashima A, Ito M, Takahashi Y, Saito H. The frequency of ovulation from the affected ovary decreases following laparoscopic cystectomy in infertile women with unilateral endometrioma during a natural cycle. J Assist Reprod Genet. 2008;25:239–244. Somigliana E, Infantino M, Benedetti F, Arnoldi M, Calanna G, Ragni G. The presence of ovarian endometriomas is associated with a reduced responsiveness to gonadotropins. Fertil Steril. 2006 Jul;86(1):192–6. Benaglia L, Bermejo A, Somigliana E, Faulisi S, Ragni G, Fedele L, Garcia-Velasco JA. In vitro fertilization outcome in women with unoperated bilateral endometriomas. Fertil Steril. 2013 May;99(6):1714–9. Hamdan M, Dunselman G, Li TC, Cheong Y. The impact of endometrioma on IVF/ICSI outcomes: a systematic review and meta-analysis. Hum Reprod Update. 2015 Nov-Dec;21(6):809–25. Carvahlo L, nataraj N, Rao J, Khetarpal S, Abrao SM, Agarwal A. Seven ways to preserve female fertility in patients with endometriosis. Expert Rev Obstet Gynecol. 2012;7930:227–240. Downloads Published Issue Section License Copyright (c) 2017 Małgorzata Agnieszka Szczepańska, Paweł P. Jagodziński, Ewa Wender-Ożegowska This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosisendometrioma

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (11)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK