The Role of Hysterectomy in the Management of Endometriosis

Endometriosis is a complex, chronic disorder that has the potential to produce long-term negative impact on the life and function of patients who carry this diagnosis. Endometriosis is thought to impact up to 10 to 15% of women across the globe and up to 90% of patients with pelvic pain. Yet, many questions remain regarding the true pathogenesis of this disease, as well as the best approach to surveillance and treatment. What we do know is that, as there remains no cure for endometriosis, management of this disease is best achieved with a longitudinal approach, with consideration of immediate disease features and other potential sequelae. The ideal treatment approach typically involves more conservative lifestyle changes, including dietary modifications, and incorporation of medication therapy, typically at the very least involving some form of hormone suppression therapy. The role of surgery remains dependent on both the patient's clinical course and the provider. Here, we explore both the known and the unknown in endometriosis management, with key updates on the potential implications of hysterectomy. Publication History Article published online: 09 December 2025 © 2025. Thieme. All rights reserved. Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USA -

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