Prostaglandins and menstrual disorders.

M.G. Elder
In: BMJ · 1983 · vol. 287(6394) , pp. 703–704 · doi:10.1136/bmj.287.6394.703 · PMID:6412789 · W2018067634
editorial OA: bronze CC0 ⤵ 2 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This paper investigates thiazide diuretic-induced hypokalemia, recommending potassium-sparing diuretics for control and further investigation for primary aldosteronism when needed.

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Abstract

investigating patients with inconsistent hypokalaemia or mild hypokalaemia taking thiazide diuretics, and in these circumstances the more reasonable approach is to attempt control with a regimen which includes a potassium retaining diuretic. Where either the raised blood pressure or the low serum potassium concentration cannot be adequately controlled more intensive investigation for primary aldosteronism in a special centre will be needed. With these guidelines the occasional patient with surgically correctable primary aldosteronism will be missed, but the cost of such an error in terms of patient morbidity or mortality will be extremely small.

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chemicals 1
prostaglandin

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