Epidural or intrathecal morphine for post-operative analgesia following laparoscopic endometriosis surgery

Vijaya Kiran Shetty, Vikas Gupta, Kiran Shetty
In: International Journal of Medical Anesthesiology · 2022 · vol. 5(3) , pp. 27–32 · doi:10.33545/26643766.2022.v5.i3a.358 · W4312580183
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⚙ AI-generated summary by claude@2026-06, 2026-06-12 ⓘ

Single intrathecal morphine injection provides safe and effective post-operative pain management for laparoscopic endometriosis surgery, unlike continuous epidural analgesia.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-12 · read from full text ⓘ

This paper investigates, via a literature search of Google Scholar, Cochrane (Controlled Trials Register), and PubMed, the evidence on epidural versus intrathecal morphine for postoperative analgesia after laparoscopic endometriosis surgery, focusing on outcomes such as postoperative pain and the use of PCA and opioids. After removing duplicates, 106 results were identified and 50 full-text publications were retrieved that met the inclusion criteria. The authors conclude that a single intrathecal morphine injection is reported as safe and effective for postoperative pain management, while continuous epidural analgesia is characterized as risky and difficult to manage after laparoscopic endometriosis surgery. This paper is centrally about endometriosis — it specifically reviews analgesic approaches using epidural or intrathecal morphine after laparoscopic endometriosis surgery.

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Abstract

Background: Endometriosis is the development of endometrial glands or stroma outside the uterine cavity, in the pelvis, ovaries, and fallopian tubes. Laproscopy is the most common method used in management of endometriosis and it also eliminates endometriosis-related scar tissue, implants, and cysts. Epidural or intrathecal morphine is an effective way to alleviate post-operative pain after laparoscopic endometriosis surgery.Methods: Literature search was conducted in three electronic databases-Google Scholar, Cochrane (Controlled Trials Register), and PubMed (MEDLINE/Index Medicus). Postoperative pain, epidural and intrathecal morphine, laparoscopy surgery, patient-controlled analgesia (PCA), opioids, and morphine were the search criteria used.Results: After removing duplicate studies, the search yielded 106 results. Out of which50 full-text publications that matched the inclusion criterion were retrieved.Conclusion: Single intrathecal morphine injection is safe and effective in managing post-operative pain, however continuous epidural analgesia is risky and difficult to manage after laparoscopic endometriosis surgery.
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Abstract

Background: Endometriosis is the development of endometrial glands or stroma outside the uterine cavity, in the pelvis, ovaries, and fallopian tubes. Laproscopy is the most common method used in management of endometriosis and it also eliminates endometriosis-related scar tissue, implants, and cysts. Epidural or intrathecal morphine is an effective way to alleviate post-operative pain after laparoscopic endometriosis surgery.

Methods

Literature search was conducted in three electronic databases-Google Scholar, Cochrane (Controlled Trials Register), and PubMed (MEDLINE/Index Medicus). Postoperative pain, epidural and intrathecal morphine, laparoscopy surgery, patient-controlled analgesia (PCA), opioids, and morphine were the search criteria used.

Results

After removing duplicate studies, the search yielded 106 results. Out of which50 full-text publications that matched the inclusion criterion were retrieved.

Conclusion

Single intrathecal morphine injection is safe and effective in managing post-operative pain, however continuous epidural analgesia is risky and difficult to manage after laparoscopic endometriosis surgery. DOI: https://www.doi.org/10.33545/26643766.2022.v5.i3a.358 Pages: 27-32 | Views: 2005 | Downloads: 1113 Download Full Article: Click Here How to cite this article: Dr. Vijaya Kiran Shetty, Dr. Vikas Gupta, Dr. Kiran Kumar Shetty. Epidural or intrathecal morphine for post-operative analgesia following laparoscopic endometriosis surgery. Int J Med Anesthesiology 2022;5(3):27-32. DOI: 10.33545/26643766.2022.v5.i3a.358

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endometriosis

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