Dysfunctional uterine bleeding in ovulatory women

Ronald C. Strickier
In: Postgraduate Medicine · 1985 · vol. 77(1) , pp. 235–246 · doi:10.1080/00325481.1985.11698855 · PMID:3880890 · W1444570701
article OA: closed CC0 ⤵ 3 in-corpus citations
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Ovulatory dysfunctional uterine bleeding, often due to disordered endometrial prostaglandin metabolism, can be treated with medication or hysterectomy.

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Abstract

Ovulatory dysfunctional uterine bleeding (DUB), a disease prevalent in the latter half of the reproductive years, is diagnosed when organic causes for bleeding have been excluded by clinical, laboratory, and surgical diagnostic means. Disordered prostaglandin metabolism within the endometrium explains most cases of DUB. Nonsteroidal antiinflammatory drugs, oral contraceptives, and oral progestin are effective medical alternatives for women who wish to retain their uterus or to avoid surgery. Hysterectomy is a rapid cure for DUB and is a therapy that is acceptable to many, if not most, women.

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