Estradiol valerate and estradiol valerate/dienogest (natazia) tablets: the first four-phasic oral contraceptive.
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This article reviews the indications, pharmacology, clinical trials, adverse effects, drug interactions, contraindications, warnings, dosage, and cost of the first four-phasic oral contraceptive, estradiol valerate and estradiol valerate/dienogest (Natazia) tablets.
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Abstract
This article focuses upon the May 2010 FDA approved estradiol valerate and estradiol valerate/dienogest (Natazia) tablets which is the first four-phasic oral contraceptive. It discusses: the indications and usage the clinical pharmacology including mechanism of action and pharmacokinetics clinical trials adverse drug effects drug interactions contraindications warnings dosage and administration and cost.
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Cites (4)
- Bleeding pattern and cycle control with an estradiol-based oral contraceptive: a seven-cycle, randomized comparative trial of estradiol valerate/dienogest and ethinyl estradiol/levonorgestrel 2009
- Efficacy and safety of a novel oral contraceptive based on oestradiol (oestradiol valerate/dienogest): A Phase III trial 2009
- Ovulation inhibition with four variations of a four-phasic estradiol valerate/dienogest combined oral contraceptive: results of two prospective, randomized, open-label studies 2008
- Pharmacokinetics of an oral contraceptive containing oestradiol valerate and dienogest 2009
References (6)
- Bleeding pattern and cycle control with an estradiol-based oral contraceptive: a seven-cycle, randomized comparative trial of estradiol valerate/dienogest and ethinyl estradiol/levonorgestrel via openalex
- Efficacy and safety of a novel oral contraceptive based on oestradiol (oestradiol valerate/dienogest): A Phase III trial via openalex
- Ovulation inhibition with four variations of a four-phasic estradiol valerate/dienogest combined oral contraceptive: results of two prospective, randomized, open-label studies via openalex
- Pharmacokinetics of an oral contraceptive containing oestradiol valerate and dienogest via openalex
- doi:10.1037/e605102007-001 via openalex
- doi:10.1212/wnl.66.66_suppl_3.s29 via openalex
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- openalex
- last seen: 2026-05-10T11:57:47.865992+00:00
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