Gefäßflächenindex (GFI) und Gefäßdichteindex (GDI) des Endometriums von Patientinnen mit und ohne Endometriose auf der Chorioallantoismembran (CAM)
This study found that the vascular surface index and vascular density index of endometrial tissue from patients with and without endometriosis increased over time when cultured on the chorioallantoic membrane, but did not differ between the patient groups.
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This study utilized the chorioallantoic membrane model to compare angiogenesis in endometrial tissue from patients with and without endometriosis. Researchers transplanted endometrial samples and native membranes, measuring vascular area and density indices over a 96-hour culture period using computer-assisted analysis. The results indicated that while both indices increased significantly over time for all groups, there were no statistical differences between the endometrium of patients with endometriosis and those without. Consequently, the authors concluded that angiogenesis is a fundamental requirement for implantation but is likely regulated by factors other than intrinsic vascular growth capacity differences between these groups. This paper is centrally about endometriosis — specifically comparing vascularization metrics of endometrial tissue from affected versus unaffected patients.
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- openalex
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- unpaywall
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