Primary Peritoneal Clear Cell Carcinoma Versus Ovarian Carcinoma Versus Malignant Transformation of Endometriosis

Luigi Insabato, Insabato L, Valentina Natella, Natella V, Somma A, Anna Somma, Persico M, Marcello Persico, Luigi Camera, Nunzia Simona Losito, Simona Losito, Losito NS, Masone S, Stefania Masone
International journal of surgical pathology · 2015 · vol. 23(3) , pp. 211–216 · doi:10.1177/1066896915573567 · PMID:25715342 · W2014516417
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This case report details a rare instance of primary peritoneal clear cell carcinoma in a 49-year-old woman, highlighting diagnostic challenges in distinguishing it from ovarian carcinoma and other peritoneal tumors.

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Abstract

Peritoneum is a site for both primary and secondary tumors. Primary peritoneal tumors are fairly rare. The most common primary tumors of the peritoneum are malignant mesothelioma and serous papillary adenocarcinoma. Clear cell carcinoma of the peritoneum is extremely rare and often misdiagnosed as mesothelioma, serous carcinoma, or metastatic adenocarcinoma, so it represents a diagnostic challenge for both clinicians and pathologists. Up to date, to the best of our knowledge, only 11 cases of primary peritoneal clear cell carcinoma have been reported in the English literature. Distinguishing this tumor of the peritoneum versus ovarian carcinoma can be problematic. Herein, we report a rare case of primary peritoneal clear cell carcinoma occurring in a 49-year-old woman, along with a review of the literature.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma, Clear Cell Peritoneal Neoplasms Adenocarcinoma, Clear Cell Diagnosis, Differential Endometriosis Endometriosis Female Humans Middle Aged Ovarian Neoplasms Ovarian Neoplasms Peritoneal Neoplasms

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License: CC0 · commercial use OK