Abdominal tuberculosis masquerading as ovarian carcinoma in a Caucasian woman: a diagnostic challenge

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A 37-year-old woman with abdominal distension and elevated CA-125 levels, initially suspected to have ovarian carcinoma, was diagnosed with abdominal tuberculosis through biopsy and whole genome sequencing.

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Abstract

We present a case of a 37-year-old Caucasian woman with abdominal distension and loss of weight. She was initially presumed to be a case of ovarian malignancy due to an elevated serum cancer antigen 125 (CA 125) level and imaging of abdomen and pelvis that showed ascites and bulky ovaries. However, histological examination of biopsy later revealed it to be a case of abdominal tuberculosis (AbT). Ascitic fluid was also found to be positive for Mycobacterium tuberculosis by whole genome sequencing. The patient was started on antituberculosis treatment following which she showed a significant improvement in her symptoms.

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MeSH descriptors

Ovarian Neoplasms Ovarian Neoplasms Tuberculosis, Lymph Node Tuberculosis, Lymph Node Abdomen Abdomen Adult Ascites Ascites Ascites CA-125 Antigen Carcinoma, Ovarian Epithelial Carcinoma, Ovarian Epithelial Diagnosis, Differential Female Humans

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europepmc
last seen: 2026-10-18T09:30:06.152893+00:00
pubmed
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