Malignancy arising in residual endometriosis following hysterectomy and hormone replacement therapy

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AI-generated summary by claude@2026-06, 2026-06-07

This paper reports on two women with endometrial adenocarcinoma arising in residual endometriosis after hysterectomy and unopposed estrogen therapy, summarizing these rare cases and related literature.

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Abstract

Two women with adenocarcinoma of the endometrium and a past history of disseminated pelvic endometriosis presented with vaginal bleeding. One also had obstructive uropathy. The two patients had undergone total abdominal hysterectomy with removal of one or both ovaries three and 13 years previously and subsequently were treated with unopposed oestrogen replacement therapy. Adenocarcinoma of the endometrium following endometriosis is a rare condition and few cases are reported in the literature. A summary of the cases and related literature are presented.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Endometriosis Pelvic Neoplasms Adenocarcinoma Adenocarcinoma Adenocarcinoma Diagnosis, Differential Endometriosis Estrogen Replacement Therapy Female Humans Hysterectomy Middle Aged Pelvic Neoplasms Pelvic Neoplasms Pelvic Neoplasms

Citation neighborhood

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Cited by (8)

Source provenance

europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:12:26.305326+00:00
unpaywall
last seen: 2026-06-13T06:42:57.164913+00:00
License: CC0 · commercial use OK