ENDOMETRIOSIS: ETIOPATHOGENESIS, EPIDEMIOLOGY, DIAGNOSIS AND THE CURRENT STATE OF TREATMENT (LITERATURE REVIEW AND STATISTICAL ANALYSIS)

Boymirzayeva Diyora Anvarjon qizi
2026 · doi:10.5281/zenodo.20624189 · W7164190260
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⚙ AI-generated summary by claude@2026-07, 2026-07-09 ⓘ

This review synthesizes contemporary data on endometriosis, finding it affects 10% of reproductive-age women, has long diagnostic delays, causes infertility in 30-40%, and has significant impacts on quality of life and the economy.

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This paper is a literature review with statistical synthesis of contemporary evidence on endometriosis, covering etiopathogenesis, epidemiology, diagnosis, and current treatment approaches by integrating data from Global Burden of Disease studies, meta-analyses, and major clinical trials. It reports that endometriosis affects about 10% of women of reproductive age, with an average diagnostic delay of 6.6–9.7 years, and infertility in roughly 30–40% of patients, while summarizing comparative efficacy and limitations of hormonal therapies, surgery, and assisted reproductive technologies. The paper’s main caveat is that it is a review and statistical synthesis rather than new original primary data, so conclusions depend on the quality and comparability of the included studies. This paper is centrally about endometriosis — it focuses on endometriosis etiopathogenesis, epidemiology, diagnosis, and the state of current treatment.

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Abstract

This article provides a systematic review and statistical analysis of contemporary scientific data on endometriosis, covering its epidemiology, etiopathogenetic theories, diagnostic approaches and treatment strategies. Statistical evidence from the Global Burden of Disease (GBD) studies, meta-analyses and major clinical trials is synthesized. Endometriosis affects approximately 10% of women of reproductive age, with a mean diagnostic delay of 6.6–9.7 years, and infertility observed in 30–40% of patients. The efficacy and limitations of hormonal therapy (progestins, GnRH agonists and antagonists), surgery and assisted reproductive technologies are compared. The detrimental impact of the disease on quality of life and the economy is substantiated by statistical data.
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ENDOMETRIOSIS: ETIOPATHOGENESIS, EPIDEMIOLOGY, DIAGNOSIS AND THE CURRENT STATE OF TREATMENT (LITERATURE REVIEW AND STATISTICAL ANALYSIS) Authors/Creators - 1. Student of Impuls Medical Institute Description This article provides a systematic review and statistical analysis of contemporary scientific data on endometriosis, covering its epidemiology, etiopathogenetic theories, diagnostic approaches and treatment strategies. Statistical evidence from the Global Burden of Disease (GBD) studies, meta-analyses and major clinical trials is synthesized. Endometriosis affects approximately 10% of women of reproductive age, with a mean diagnostic delay of 6.6–9.7 years, and infertility observed in 30–40% of patients. The efficacy and limitations of hormonal therapy (progestins, GnRH agonists and antagonists), surgery and assisted reproductive technologies are compared. The detrimental impact of the disease on quality of life and the economy is substantiated by statistical data. Files 1338-1343.pdf Files (256.9 kB) | Name | Size | Download all | |---|---|---| | md5:cebcef39e7df194ee611d541d56594e7 | 256.9 kB | Preview Download | Additional details References - 1.Harder C., et al. Assessing the true prevalence of endometriosis: A narrative review of literature data // International Journal of Gynecology & Obstetrics. — 2024. - 2.GBD 2021. Global, regional, and national burden of endometriosis among women of reproductive age, 1990–2021 // Frontiers in Global Women's Health. — 2025. - 3.Global prevalence of adenomyosis and endometriosis: a systematic review and meta-analysis // PubMed (PMID: 41257733). — 2025. - 4.Taylor H.S., Kotlyar A.M., Flores V.A. Endometriosis is a chronic systemic disease: clinical challenges and novel innovations // The Lancet. — 2021. — Vol. 397. — P. 839–852. - 5.Zondervan K.T., Becker C.M., Missmer S.A. Endometriosis // New England Journal of Medicine. — 2020. — Vol. 382, No. 13. — P. 1244–1256.

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