Die primäre umbilikale Endometriose

The paper reports two clinical cases of primary umbilical endometriosis, a rare extragenital form of endometriosis with an incidence cited as ~0.5–1%, presenting to an endometriosis clinic within 11 months. In Case 1, a 26-year-old with a painful umbilical lesion that bled during menstruation underwent complete excision with histologic confirmation of extragenital endometriosis; no prior abdominal surgery was reported, and ultrasound could not delineate the lesion. In Case 2, a 30-year-old with cyclical bleeding and typical endometriosis symptoms had a palpable/ultrasound-visible umbilical mass despite no history of abdominal surgery and initially opted for conservative management with a dienogest-containing preparation. The authors note that endometriosis pathogenesis remains theoretical, with current guideline framing that existing theories are not fully satisfactory and may require integration with genetic defects and epigenetic phenomena. This paper is centrally about endometriosis — it focuses specifically on primary umbilical (extragenital) endometriosis case reports.

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