Immunohistochemical Evaluation of Chronic Endometritis by CD138, CD3 and CD20

Tarunpreet Kaur Sarpal, Ranjeev Bhagat, Rajpal Singh Punia, Pavithra H N Pavithra H N, Bharti Goyal, Uma Handa
In: Annals of Pathology and Laboratory Medicine · 2019 · vol. 6(8) , pp. A402–406 · doi:10.21276/apalm.2625 · W3039287240
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⚙ AI-generated summary by claude@2026-06, 2026-06-10 ⓘ

This study evaluated chronic endometritis using immunohistochemistry to detect plasma cells (CD138) and lymphocytes (CD3, CD20) in endometrial biopsies.

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Abstract

Background: Chronic inflammation of endometrium is often clinically silent but may present as abnormal uterine bleeding, dyspareunia, infertility, leucorrhoea and sometimes urinary symptoms. The diagnosis is often rendered on histopathological examination of endometrial biopsy showing chronic inflammatory infiltrate in general and plasma cells in particular. In order to identify scant plasma cells and lymphocytes in the chronic endometritis, immunohistochemistry is increasing being used to confirm the diagnosis.

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Condition tags

dyspareuniainfertilitydisambig:endometritis

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last seen: 2026-06-04T00:00:01.174412+00:00
License: CC0 · commercial use OK