The Value of ESWAN in Diagnostic of Adenomyosis and Related Study about Dysmenorrheal

In: Research Square · 2019 · doi:10.21203/rs.2.14073/v1 · W4213073031
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Abstract

Abstract Background This retrospective study aimed (1) to evaluate the value of enhanced T2 star-weighted angiography (ESWAN) in diagnosis Adenomyosis(AM). And (2) to estimate the differences of focal AM patients lesion and the peripheral tissues region. And (3) analysis the correlation between the multiple indices of ESWAN and dysmenorrheal, focal AM lesion ratio.Methods Traditional MRI and ESWAN were performed on seventy-two clinically–diagnosed AM patients (fifty for focal and twenty-two for diffuse AM), and fifty-six normal adult woman . The ESWAN indices (magnitude value, phase value, R2* value and T2* value) measured on different regions of interest (ROIs) were analyzed. Measured the focal AM lesion size and Uterine volume by tradition MRI, and using visual analogue scale(VAS) measured dysmenorrheal level.Results The magnitude value, phase value, R2* value and T2* value of focal AM, diffuse AM, peripheral tissue in focal AM and normal myometrium were respectively 1176.20±367.70/1286.51±349.49/1139.61±426.69/1685.94±407.14, 0.0114±0.0438/0.0138±0.0182/0.0296±0.0858/0.0433±0.0869, 26.39±3.36/27.40±2.36/27.24±4.60/22.54±5.03, 39.83±5.47/37.49±3.48/38.67±7.09/43.39±8.94. The ESWAN indices by one-way ANOVA showed statistical difference with the normal myometrium and focal and diffuse AM(0.000, 0.027, 0.000, 0.002). Compared with the peripheral tissue, the focal AM indices were no statistical difference. The correlation between the dysmenorrheal level and phase value were statistical difference(0.018).Conclusions ESWAN sequence has fractional value in diagnosis AM by different indices. And the dysmenorrheal level could react the AM feature in certain degree.

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adenomyosis

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