Stem Cells of the Endometrium: A Leap towards Regenerative Medicine

Indumathi Somasundaram
In: Women's Health · 2017 · vol. 4(6) · doi:10.15406/mojwh.2017.04.00102 · W2770543854
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Abstract

Stem cells derived from umbilical cord, peripheral blood, bone marrow and adipose tissue areroutinely been used to treat disease today. Nevertheless, the existence of adult stem cells and their immense potency from different sources such as placenta, endometrium, fallopian tube, amniotic fluid, amniotic membrane, menstrual blood have been discovered in the past decades. Stem cells derived from female reproductive sources, especially endometrium are gaining special interest in recent years. It is a dynamic tissue engaged in the coordinated functions of proliferation, differentiation and menstrual shedding. Upper functional is layer which sheds during menstruation is later regenerated efficiently by the basal is layer of the endometrial tissue, suggesting the presence of highly potential stem cell population. In addition, endometrium can easily be obtained from hysterectomy (surgical discards of uterus), thus making it easier to collect. Besides, they are reliable, accessible, non-invasive and ideal alternate potent source of stem cells for therapeutic interventions. Thus, the aim of this present review is to highlight the significance of these stem cells isolated from endometrium for their implications in regenerative stem cell therapeutics.

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