Laparoscopic Ultrasound-Guided Radiofrequency Ablation of Uterine Fibroids

Andrea Milić, Andrea Milic, Milic A, Murray R Asch, Murray Asch, Asch MR, P. Hawrylyshyn, Hawrylyshyn PA, Peter A Hawrylyshyn, Lisa Allen, Allen LM, Lisa M Allen, Terence J. Colgan, Colgan TJ, Kachura JR, John R. Kachura, Hayeems EB, Eran Hayeems, Eran B Hayeems
Cardiovascular and interventional radiology · 2006 · vol. 29(4) , pp. 694–698 · doi:10.1007/s00270-005-0045-9 · PMID:16502165 · W2072552504
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Laparoscopic ultrasound-guided radiofrequency ablation using multiprobe-array electrodes was technically successful in three of four patients with symptomatic uterine fibroids, achieving complete ablation and symptom improvement in two patients.

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This study evaluated the technical feasibility and clinical outcomes of laparoscopic ultrasound-guided radiofrequency ablation for symptomatic uterine fibroids smaller than 6 cm in a small cohort of four patients. While initial procedural success was observed in three cases with complete ablation on MRI, symptom relief was inconsistent, and one patient experienced worsening symptoms due to recurrent fibroid growth. Notably, a third patient who initially appeared technically successful but reported no improvement was subsequently diagnosed with adenomyosis after the procedure failed to alleviate her condition. Relevance to endometriosis: The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Four patients with symptomatic uterine fibroids measuring less than 6 cm underwent laparoscopic ultrasound-guided radiofrequency ablation (RFA) using multiprobe-array electrodes. Follow-up of the treated fibroids was performed with gadolinium-enhanced magnetic resonance imaging (MRI) and patients' symptoms were assessed by telephone interviews. The procedure was initially technically successful in 3 of the 4 patients and MRI studies at 1 month demonstrated complete fibroid ablation. Symptom improvement, including a decrease in menstrual bleeding and pain, was achieved in 2 patients at 3 months. At 7 months, 1 of these 2 patients experienced symptom worsening which correlated with recurrent fibroid on MRI. The third, initially technically successfully treated patient did not experience any symptom relief after the procedure and was ultimately diagnosed with adenomyosis. Our preliminary results suggest that RFA is a technically feasible treatment for symptomatic uterine fibroids in appropriately selected patients.
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Abstract

Four patients with symptomatic uterine fibroids measuring less than 6 cm underwent laparoscopic ultrasound-guided radiofrequency ablation (RFA) using multiprobe-array electrodes. Follow-up of the treated fibroids was performed with gadolinium-enhanced magnetic resonance imaging (MRI) and patients’ symptoms were assessed by telephone interviews. The procedure was initially technically successful in 3 of the 4 patients and MRI studies at 1 month demonstrated complete fibroid ablation. Symptom improvement, including a decrease in menstrual bleeding and pain, was achieved in 2 patients at 3 months. At 7 months, 1 of these 2 patients experienced symptom worsening which correlated with recurrent fibroid on MRI. The third, initially technically successfully treated patient did not experience any symptom relief after the procedure and was ultimately diagnosed with adenomyosis. Our preliminary results suggest that RFA is a technically feasible treatment for symptomatic uterine fibroids in appropriately selected patients. Similar content being viewed by others

References

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Acknowledgements

The grant support for this study was provided by Boston Scientific. In addition, M.R.A. is a paid consultant for Boston Scientific. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Milic, A., Asch, M.R., Hawrylyshyn, P.A. et al. Laparoscopic Ultrasound-Guided Radiofrequency Ablation of Uterine Fibroids. Cardiovasc Intervent Radiol 29, 694–698 (2006). https://doi.org/10.1007/s00270-005-0045-9 Published: Issue date: DOI: https://doi.org/10.1007/s00270-005-0045-9

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MeSH descriptors

Catheter Ablation Leiomyoma Uterine Neoplasms Adult Catheter Ablation Female Humans Laparoscopy Leiomyoma Leiomyoma Leiomyoma Middle Aged Ultrasonography Uterine Neoplasms Uterine Neoplasms Uterine Neoplasms

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