Laparoscopic Ultrasound-Guided Radiofrequency Ablation of Uterine Fibroids

Andrea Milić, Andrea Milic, Milic A, Murray R Asch, Murray Asch, Asch MR, P. Hawrylyshyn, Hawrylyshyn PA, Peter A Hawrylyshyn, Lisa Allen, Allen LM, Lisa M Allen, Terence J. Colgan, Colgan TJ, Kachura JR, John R. Kachura, Hayeems EB, Eran Hayeems, Eran B Hayeems
Cardiovascular and interventional radiology · 2006 · vol. 29(4) , pp. 694–698 · doi:10.1007/s00270-005-0045-9 · PMID:16502165 · W2072552504
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Laparoscopic ultrasound-guided radiofrequency ablation using multiprobe-array electrodes was technically successful in three of four patients with symptomatic uterine fibroids, achieving complete ablation and symptom improvement in two patients.

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Abstract

Four patients with symptomatic uterine fibroids measuring less than 6 cm underwent laparoscopic ultrasound-guided radiofrequency ablation (RFA) using multiprobe-array electrodes. Follow-up of the treated fibroids was performed with gadolinium-enhanced magnetic resonance imaging (MRI) and patients' symptoms were assessed by telephone interviews. The procedure was initially technically successful in 3 of the 4 patients and MRI studies at 1 month demonstrated complete fibroid ablation. Symptom improvement, including a decrease in menstrual bleeding and pain, was achieved in 2 patients at 3 months. At 7 months, 1 of these 2 patients experienced symptom worsening which correlated with recurrent fibroid on MRI. The third, initially technically successfully treated patient did not experience any symptom relief after the procedure and was ultimately diagnosed with adenomyosis. Our preliminary results suggest that RFA is a technically feasible treatment for symptomatic uterine fibroids in appropriately selected patients.
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Abstract

Four patients with symptomatic uterine fibroids measuring less than 6 cm underwent laparoscopic ultrasound-guided radiofrequency ablation (RFA) using multiprobe-array electrodes. Follow-up of the treated fibroids was performed with gadolinium-enhanced magnetic resonance imaging (MRI) and patients’ symptoms were assessed by telephone interviews. The procedure was initially technically successful in 3 of the 4 patients and MRI studies at 1 month demonstrated complete fibroid ablation. Symptom improvement, including a decrease in menstrual bleeding and pain, was achieved in 2 patients at 3 months. At 7 months, 1 of these 2 patients experienced symptom worsening which correlated with recurrent fibroid on MRI. The third, initially technically successfully treated patient did not experience any symptom relief after the procedure and was ultimately diagnosed with adenomyosis. Our preliminary results suggest that RFA is a technically feasible treatment for symptomatic uterine fibroids in appropriately selected patients. Similar content being viewed by others

References

Goldfarb HA (2000) Myoma coagulation (myolysis). Obstet Gynecol Clin North Am 27:421–430 Iverson RE Jr, Chelmow D, Strohbehn K, et al. (1996) Relative morbidity of abdominal hysterectomy and myomectomy for management of uterine leiomyomas. Obstet Gynecol 88:415–419 Olive DL (2000) Review of evidence for treatment of leiomyomata. Environ Health Perspect 108:841–843 LeVeen RF (1997) Laser hyperthermia and radiofrequency ablation of hepatic lesions. Semin Interv Radiol 14:313–324 Chan RP, Asch M, Kachura J, et al. (2002) Radiofrequency ablation of malignant hepatic neoplasms. Can Assoc Radiol J 53:272–278 Dupuy DE, Goldberg SN (2001) Image-guided radiofrequency tumor ablation: Challenges and opportunities. Part II. J Vasc Interv Radiol 12:1135–1148 Kosari K, Gomes M, Hunter D, et al. (2002) Local, intrahepatic, and systemic recurrence patterns after radiofrequency ablation of hepatic malignancies. J Gastrointest Surg 6:255–263 Goldfarb HA (1995) Bipolar laparoscopic needles for myoma coagulation. J Am Assoc Gynecol Laparosc 2:175–179 Nisolle M, Smets M, Gillerot S (1993) Laparoscopic myolysis with the Nd:YAG laser. J Gynecol Surg 9:95–99 Pelage JP, Guaou NG, Jha RC, et al. (2004) Uterine fibroid tumors: Long-term MR imaging outcome after embolization. Radiology 230:803–809 Omary RA, Vasireddy S, Chrisman HB, et al. (2002) The effect of pelvic MR imaging on the diagnosis and treatment of women with presumed symptomatic uterine fibroids. J Vasc Interv Radiol 13:1149–1153 Colgan TJ, Pron G, Mocarski EJ, et al. (2003) Pathologic features of uteri and leiomyomas following uterine artery embolization for leiomyomas. Am J Surg Pathol 27:177–177 Rhim H, Dodd GD 3rd, Chintapalli KN, et al. (2004) Radiofrequency thermal ablation of abdominal tumors: Lessons learned from complications. Radiographics 24:41–52

Acknowledgements

The grant support for this study was provided by Boston Scientific. In addition, M.R.A. is a paid consultant for Boston Scientific. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Milic, A., Asch, M.R., Hawrylyshyn, P.A. et al. Laparoscopic Ultrasound-Guided Radiofrequency Ablation of Uterine Fibroids. Cardiovasc Intervent Radiol 29, 694–698 (2006). https://doi.org/10.1007/s00270-005-0045-9 Published: Issue date: DOI: https://doi.org/10.1007/s00270-005-0045-9

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MeSH descriptors

Catheter Ablation Leiomyoma Uterine Neoplasms Adult Catheter Ablation Female Humans Laparoscopy Leiomyoma Leiomyoma Leiomyoma Middle Aged Ultrasonography Uterine Neoplasms Uterine Neoplasms Uterine Neoplasms

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