{"paper_id":"2c595864-dc63-41b3-b9c6-7c75e969d04b","body_text":"Abstract\nFour patients with symptomatic uterine fibroids measuring less than 6 cm underwent laparoscopic ultrasound-guided radiofrequency ablation (RFA) using multiprobe-array electrodes. Follow-up of the treated fibroids was performed with gadolinium-enhanced magnetic resonance imaging (MRI) and patients’ symptoms were assessed by telephone interviews. The procedure was initially technically successful in 3 of the 4 patients and MRI studies at 1 month demonstrated complete fibroid ablation. Symptom improvement, including a decrease in menstrual bleeding and pain, was achieved in 2 patients at 3 months. At 7 months, 1 of these 2 patients experienced symptom worsening which correlated with recurrent fibroid on MRI. The third, initially technically successfully treated patient did not experience any symptom relief after the procedure and was ultimately diagnosed with adenomyosis. Our preliminary results suggest that RFA is a technically feasible treatment for symptomatic uterine fibroids in appropriately selected patients.\nSimilar content being viewed by others\nReferences\nGoldfarb HA (2000) Myoma coagulation (myolysis). Obstet Gynecol Clin North Am 27:421–430\nIverson RE Jr, Chelmow D, Strohbehn K, et al. (1996) Relative morbidity of abdominal hysterectomy and myomectomy for management of uterine leiomyomas. Obstet Gynecol 88:415–419\nOlive DL (2000) Review of evidence for treatment of leiomyomata. Environ Health Perspect 108:841–843\nLeVeen RF (1997) Laser hyperthermia and radiofrequency ablation of hepatic lesions. Semin Interv Radiol 14:313–324\nChan RP, Asch M, Kachura J, et al. (2002) Radiofrequency ablation of malignant hepatic neoplasms. Can Assoc Radiol J 53:272–278\nDupuy DE, Goldberg SN (2001) Image-guided radiofrequency tumor ablation: Challenges and opportunities. Part II. J Vasc Interv Radiol 12:1135–1148\nKosari K, Gomes M, Hunter D, et al. (2002) Local, intrahepatic, and systemic recurrence patterns after radiofrequency ablation of hepatic malignancies. J Gastrointest Surg 6:255–263\nGoldfarb HA (1995) Bipolar laparoscopic needles for myoma coagulation. J Am Assoc Gynecol Laparosc 2:175–179\nNisolle M, Smets M, Gillerot S (1993) Laparoscopic myolysis with the Nd:YAG laser. J Gynecol Surg 9:95–99\nPelage JP, Guaou NG, Jha RC, et al. (2004) Uterine fibroid tumors: Long-term MR imaging outcome after embolization. Radiology 230:803–809\nOmary RA, Vasireddy S, Chrisman HB, et al. (2002) The effect of pelvic MR imaging on the diagnosis and treatment of women with presumed symptomatic uterine fibroids. J Vasc Interv Radiol 13:1149–1153\nColgan TJ, Pron G, Mocarski EJ, et al. (2003) Pathologic features of uteri and leiomyomas following uterine artery embolization for leiomyomas. Am J Surg Pathol 27:177–177\nRhim H, Dodd GD 3rd, Chintapalli KN, et al. (2004) Radiofrequency thermal ablation of abdominal tumors: Lessons learned from complications. Radiographics 24:41–52\nAcknowledgements\nThe grant support for this study was provided by Boston Scientific. In addition, M.R.A. is a paid consultant for Boston Scientific.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nRights and permissions\nAbout this article\nCite this article\nMilic, A., Asch, M.R., Hawrylyshyn, P.A. et al. Laparoscopic Ultrasound-Guided Radiofrequency Ablation of Uterine Fibroids. Cardiovasc Intervent Radiol 29, 694–698 (2006). https://doi.org/10.1007/s00270-005-0045-9\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/s00270-005-0045-9","source_license":"CC0","license_restricted":false}