Endometriose – Entscheidungshilfen für das Vorgehen bei akuten und rezidivierenden Beschwerden

In: Die Gynäkologie · 2024 · vol. 57(9) , pp. 606–612 · doi:10.1007/s00129-024-05271-5 · W4401934150
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This article discusses treatment options for endometriosis, emphasizing individualized, participatory decision-making by considering patient factors in certified centers.

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This article discusses decision aids for managing acute and recurrent complaints in the context of endometriosis, noting increasing prevalence from 2012 to 2022 and persistent diagnostic delays of up to seven years. Drawing on guideline-based causal hormone therapy as well as complementary treatment options, it emphasizes an individualized, interprofessional approach in certified endometriosis centers, developed through participatory decision-making that incorporates comorbidities, personality, patient goals, and life situation. A key caveat explicitly stated is that the authors did not conduct new human or animal studies for this contribution. Relevance to endometriosis: the paper focuses directly on endometriosis management decisions for acute and recurrent symptoms and treatment-option discussions, though adenomyosis is not specifically addressed.

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Zusammenfassung Das erhöhte Bewusstsein für das Krankheitsbild Endometriose spiegelt sich in dem Anstieg der Endometrioseprävalenz zwischen 2012 und 2022 wieder. Trotzdem geht man von einer bis zu 7-jährigen Diagnoseverspätung aus. Betroffene junge Frauen leiden nicht nur an den somatischen Beschwerden, sondern auch auf psychischer Ebene durch eine mögliche Missachtung des Leidendrucks. Neben der kausalen leitliniengerechten Hormontherapie, die von den Patientinnen häufig nicht favorisiert wird, sind zusätzliche komplementäre Therapieoptionen vorhanden. Gerade in zertifizierten Endometriose-Zentren können interdisziplinäre Ansätze erarbeitet werden. Ziel ist es, im Prozess einer partizipativen Entscheidungsfindung, in dem auch weitere somatische Erkrankungen, die Persönlichkeit, Wünsche und die Lebenssituation der Patientin berücksichtigt werden, ein individualisiertes Behandlungskonzept zu erarbeiten. In diesem Beitrag werden Therapieoptionen dargelegt und diskutiert. Abstract Current national figures show a clear increase in the prevalence of endometriosis from 2012 to 2022. The diagnosis is still frequently made after a delay. Those affected are not only impaired by physical symptoms but also at the mental level due to the disregard of their suffering. In many cases not only one form of treatment is the right one and many treatment options each have advantages and disadvantages. Particularly in certified endometriosis centers, interdisciplinary approaches can be combined with complementary medical measures. The aim is to develop an individualized and differentiated treatment concept in a participative decision-making process in which the personality, aims and life situation of the patient are taken into consideration. In this article the treatment options are presented and discussed. Similar content being viewed by others Literatur World Health Organisation Endometriosis – Key facts. https://www.who.int/news-room/fact-sheets/detail/endometriosis. Zugegriffen: 29. Mai 2024 Hudelist G, Fritzer N, Thomas A et al (2012) Diagnostic delay for endometriosis in Austria and Germany: causes and possible consequences. Hum Reprod 27(12):3412–3416 Kohring C, Holstiege J, Heuer J, Dammertz L, Brandes I, Mechsner S, Akmatov MK (2024) Endometriose in der vertragsärztlichen Versorgung – Regionale und zeitliche Trends im Zeitraum 2012 bis 2022. Zentralinstitut für die kassenärztliche Versorgung in Deutschland (Zi). Versorgungsatlas-Bericht Nr. 24/01. Berlin https://doi.org/10.20364/VA-24.01 Sims OT, Gupta J, Missmer SA et al (2021) Stigma and Endometriosis: a brief overview and recommendations to improve psychosocial well-being and diagnostic delay. Int J Environ Res Public Health 18(15) van der Zanden M, de Kok L, Nelen WLDM et al (2021) Strengths and weaknesses in the diagnostic process of endometriosis from the patients’ perspective: a focus group study. 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Int J Gynaecol Obstet 125(3):270–274. https://doi.org/10.1016/j.ijgo.2013.11.017 Rasp E et al (2024) Psychiatric disorders and mortality due to external causes following diagnosis of endometriosis at young age: a longitudinal register-based cohort study in Finland. Am J Obstetr Gynecol. https://doi.org/10.1016/j.ajog.2024.02.011 Adachi K, Takahashi K, Nakamura K, Otake A, Sasamoto N, Miyoshi Y, Shioji M, Yamamoto Y, Fujitani M, Wakimoto A, Tokuhira A, Kobayashi E, Yoshimura A, Sawada K, Kimura T (2016) Postoperative administration of dienogest for suppressing recurrence of disease and relieving pain in subjects with ovarian endometriomas. Gynecol Endocrinol 32(8):646–649. https://doi.org/10.3109/09513590.2016.1147547 Zorbas KA, Economopoulos KP, Vlahos NF (2015) Continuous versus cyclic oral contraceptives for the treatment of endometriosis: a systematic review. Arch Gynecol Obstet 292(1):37–43. https://doi.org/10.1007/s00404-015-3641-1 Guerriero S, Condous G, van den Bosch T, Valentin L, Leone FP, Van Schoubroeck D, Exacoustos C, Installé AJ, Martins WP, Abrao MS, Hudelist G, Bazot M, Alcazar JL, Gonçalves MO, Pascual MA, Ajossa S, Savelli L, Dunham R, Reid S, Menakaya U, Bourne T, Ferrero S, Leon M, Bignardi T, Holland T, Jurkovic D, Benacerraf B, Osuga Y, Somigliana E, Timmerman D (2016) systematic approach to sonographic evaluation of the pelvis in women with suspected endometriosis, including terms, definitions and measurements: a consensus opinion from the international Deep Endometriosis Analysis (IDEA) group. Ultrasound Obstet Gynecol 48(3):318–332. https://doi.org/10.1002/uog.15955 Martire FG, Giorgi M, D’Abate C, Colombi I, Ginetti A, Cannoni A, Fedele F, Exacoustos C, Centini G, Zupi E, Lazzeri L (2024) Deep infiltrating Endometriosis in adolescence: early diagnosis and possible prevention of disease progression. J Clin Med. https://doi.org/10.3390/jcm13020550 Author information Authors and Affiliations Corresponding author Ethics declarations Interessenkonflikt O. Buchweitz, A. Hackethal und C. Bormann geben an, dass kein Interessenkonflikt besteht. Für diesen Beitrag wurden von den Autor/-innen keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. Additional information Redaktion Katrin Schaudig, Hamburg Jens-Uwe Blohmer, Berlin Dietmar Schlembach, Berlin Barbara Schmalfeldt, Hamburg Hinweis des Verlags Der Verlag bleibt in Hinblick auf geografische Zuordnungen und Gebietsbezeichnungen in veröffentlichten Karten und Institutsadressen neutral. QR-Code scannen & Beitrag online lesen Rights and permissions About this article Cite this article Buchweitz, O., Hackethal, A. & Bormann, C. Endometriose – Entscheidungshilfen für das Vorgehen bei akuten und rezidivierenden Beschwerden. Gynäkologie 57, 606–612 (2024). https://doi.org/10.1007/s00129-024-05271-5 Accepted: Published: Version of record: Issue date: DOI: https://doi.org/10.1007/s00129-024-05271-5

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