Prevention of Postoperative Adhesions

Anthony A. Luciano
In: Endometriosis · 1995 · pp. 193–200 · doi:10.1007/978-1-4613-8404-5_19 · W92192989
book-chapter OA: closed CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-08 ⓘ

Peritoneal adhesions are known to cause infertility, with studies showing an inverse relationship between adhesion severity and pregnancy rates.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 ⓘ

This chapter reviews the causes and prevention of postoperative peritoneal adhesions, noting their clinical associations with bowel obstruction, pelvic pain, and infertility and citing classic evidence such as an inverse relationship between adhesion grade and pregnancy rates after tubal reconstruction. It surveys high-level evidence from experimental and clinical studies of various adhesion-prevention strategies, including intraperitoneal agents (e.g., dextran), physical barriers (e.g., absorbable Interceed TC7 and nonabsorbable Gore-Tex), and different surgical modalities and injury mechanisms, while also mentioning reported complications such as recurrent anaphylaxis to intraperitoneal dextran. A major caveat is that the cited literature spans models and contexts (animal uterine horn models, reproductive pelvic surgery, and second-look evaluations), which the chapter implicitly treats as variably comparable and therefore limits direct generalization. Relevance to endometriosis: the chapter explicitly discusses adhesion prevention in the setting of infertility and endometriosis surgery (e.g., use of Interceed TC7 in infertility and endometriosis surgery) and includes citations on adhesions after resection of ovarian endometriomas and laparoscopic management of rectovaginal endometriosis.

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