Capsaicin Inhibits Proliferation of Endometriotic Cells in vitro

Yan Wu, Wu Y, Starzinski-Powitz A, Anna Starzinski-Powitz, Anna Starzinski‐Powitz, Sun‐Wei Guo, Sun-Wei Guo, Guo SW
Gynecologic and obstetric investigation · 2008 · vol. 66(1) , pp. 59–62 · doi:10.1159/000124275 · PMID:18391504 · W2009751499
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Capsaicin inhibited the proliferation of both stromal and epithelial endometriotic cells in vitro in a dose-dependent manner, with endometriotic cells showing greater sensitivity than normal endometrial cells.

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Abstract

Treatment of immortalized stromal-like and epithelial-like endometriotic cells with capsaicin resulted in inhibition of proliferation in a concentration-dependent manner. In addition, endometriotic cells are more sensitive to capsaicin treatment than immortalized endometrial cells, suggesting that capsaicin may be an admissible drug candidate for treating endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Capsaicin Cell Proliferation Endometriosis Endometrium Endometrium Growth Inhibitors Capsaicin Cell Proliferation Dose-Response Relationship, Drug Endometriosis Endometrium Female Growth Inhibitors Humans In Vitro Techniques

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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