Chronic endometritis as a result of infectious inflammatory diseases of the uterus

In: GYNECOLOGY · 2016 · vol. 18(2) · doi:10.26442/2079-5696_18.2.44-50 · W2883408779
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This study investigated chronic endometritis, a gynecological problem linked to immune response and local endometrial immunity, and explored the use of immunomodulatory and proteolytic drugs like bovhyaluronidase azoximer for treatment.

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Abstract

Chronic endometritis is one of the most urgent problems of modern gynecology. The difficulties of verification, the lack of unity in the understanding of the nature of the inflammatory lesions of the endometrium, a symptomically uneven picture with multiple negative outcomes for reproduction - all this determines the interest in the pathogenesis, diagnosis and treatment of chronic endometritis. The treatment of endometritis, as a form of inflammatory diseases of the pelvic organs, lies in the use of antibiotic therapy. However, the formation of chronic inflammation is associated not so much with the virulence of the organism, but with the features of the immune response of host and the local immunity of the endometrium. This justifies the use in the treatment of immunomodulatory drugs and drugs with proteolytic action, aimed at preventing fibrosis and sclerosis of tissues. One of these drugs is bovhyaluronidase azoximer (Longidaze).

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