[Cytotoxic activity of NK cells in the presence of the peritoneal fluid fro women with unexplained infertility and with endometriosis related infertility].

Ginekologia polska · 1998 · vol. 69(12) , pp. 1179–82 · PMID:10224800 · W2413366374
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Peritoneal fluid from women with unexplained infertility or severe endometriosis significantly suppressed NK cell cytotoxic activity, suggesting potential immunological dysregulation in these conditions.

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Abstract

We examined peritoneal fluid obtained during laparoscopy in the aspect of its influence on cytotoxic activity of NK cells. We showed significant suppression of this activity in women with unexplained infertility. The suppression of NK activity was also present in women fertile and infertile both, with severe endometriosis. These results may indicate the immunological disorders in unexplained infertility and in endometriosis-related infertility.

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Condition tags

endometriosisinfertility

MeSH descriptors

Ascitic Fluid Cytotoxins Endometriosis Infertility, Female Infertility, Female Killer Cells, Natural Uterine Diseases Ascitic Fluid Cytotoxins Endometriosis Endometriosis Female Humans Infertility, Female Killer Cells, Natural Severity of Illness Index Uterine Diseases Uterine Diseases

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