Identification of Predictive Factors in Endometriosis for Improvement in Patient Quality of Life

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This study identified factors predictive of improved quality of life in patients with endometriosis.

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Abstract

Study objectiveTo investigate predictive factors for change in quality of life (QOL) between pre- and postoperative periods in patients with endometriosis.DesignA prospective and multicenter cohort study.SettingFive districts including a tertiary referral center and private and general public hospitals.PatientsNine hundred eighty-one patients aged 15 to 50 years underwent laparoscopic treatment (preferred approach) for endometriosis between January 2004 and December 2012.InterventionsLaparoscopic treatment for endometriosis. All revised American Fertility Society stages were included.Measurements and main resultsQOL was evaluated using the 36-Item Short Form Survey questionnaire. Factors influencing changes for each 36-Item Shorty Form Survey domain score between t0 (before surgery) and 1 year after surgery were predicted on the basis of univariate and multivariable analyses. The effect size (ES) method was used to measure changes in QOL. Univariate analysis revealed that 47% of stage IV endometriosis patients presented an improvement in the postoperative Physical Component Summary (PCS) score (ES ≥ 0.8) versus 26%, 31.3%, and 27.5% of patients with stage I, II, and III, respectively (p 0.8) versus 23% and 24% of patients without CPP, respectively (p 0.8 vs ES < 0) revealed that women with CPP were more likely to experience greater improvement in postoperative PCS and Mental Component Summary scores than women without CPP (relative risk [RR] = 2.7; 95% confidence interval [CI], 1.7-4.4; p <.001 and RR = 1.8; 95% CI, 1.2-2.8; p <.01, respectively). Accordingly, fertile patients were more likely to show higher rates of improvement in the postoperative PCS score than infertile patients (RR = 1.8; 95% CI, 1.1-3.1; p <.05).ConclusionPatients presenting with severe endometriosis and who experience higher levels of pain are more likely to show improvement in QOL after surgery. CPP is the most significant independent predictive factor for changes in QOL scores.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Endometriosis Peritoneal Diseases Peritoneal Diseases Quality of Life Adolescent Adult Chronic Pain Chronic Pain Chronic Pain Chronic Pain Cohort Studies Endometriosis Endometriosis Female Gynecologic Surgical Procedures Gynecologic Surgical Procedures Gynecologic Surgical Procedures Humans Laparoscopy

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