Endometriosis and Cardiovascular Disease: A Systematic Review

Pande Putu Firsta Widyaning
In: Asian Journal of Health Research · 2024 · vol. 3(2) , pp. 183–189 · doi:10.55561/ajhr.v3i2.173 · W4402346473
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This systematic review found that women with endometriosis have an elevated risk and incidence of cerebrovascular and cardiovascular disease, with altered lipid profiles also noted.

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This systematic review examined whether endometriosis is associated with cardiovascular disease, focusing on related factors such as atherosclerosis, cardiovascular risk, chronic inflammation, dyslipidaemia, and endothelial dysfunction. The authors searched for publications from 2017 to 2022 across multiple databases using PRISMA-P methods. They found that among women with endometriosis, four included studies reported elevated risk and incidence of cerebrovascular and cardiovascular disease, and one study reported a substantial increase in lipid profile values, a known risk factor for atherosclerosis. The paper concludes that cardiovascular disease is more likely to affect women with endometriosis, making it centrally about endometriosis — specifically the relationship between endometriosis and cardiovascular disease/cerebrovascular outcomes.

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Abstract

Introduction: Endometriosis is a chronic condition characterized by the aberrant distribution of functional tissue outside of the uterus, such as endometrial ducts and stroma. It is dependent on estrogen. Cardiovascular disease may be more prevalent in women who have endometriosis. Materials/Methods: Using the following keywords: "atherosclerosis," "cardiovascular disease," "cardiovascular risk," "chronic inflammation," "dyslipidaemia," "endometriosis," and "endothelial dysfunction," we searched for publications published between 2017 and 2022. A thorough literature search was conducted using a variety of search engines, such as PubMed, Cochrane, Springer, Science Direct, Nature, and Google Scholar. The literature selection was conducted using the recommendations of the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P).. Results: In women with endometriosis, four studies reported an elevated risk and incidence of cerebrovascular disease and cardiovascular disease. A study reported a substantial increase in the lipid profile value of patients with endometriosis, a known risk factor for the development of atherosclerosis. Conclusion: Cardiovascular disease is more likely to strike women who have endometriosis.
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Keywords

Atherosclerosis, Cardiovascular Disease, EndometriosisAbstract

Introduction

Endometriosis is a chronic condition characterized by the aberrant distribution of functional tissue outside of the uterus, such as endometrial ducts and stroma. It is dependent on estrogen. Cardiovascular disease may be more prevalent in women who have endometriosis. Materials/Methods: Using the following keywords: "atherosclerosis," "cardiovascular disease," "cardiovascular risk," "chronic inflammation," "dyslipidaemia," "endometriosis," and "endothelial dysfunction," we searched for publications published between 2017 and 2022. A thorough literature search was conducted using a variety of search engines, such as PubMed, Cochrane, Springer, Science Direct, Nature, and Google Scholar. The literature selection was conducted using the recommendations of the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P)..

Results

In women with endometriosis, four studies reported an elevated risk and incidence of cerebrovascular disease and cardiovascular disease. A study reported a substantial increase in the lipid profile value of patients with endometriosis, a known risk factor for the development of atherosclerosis.

Conclusion

Cardiovascular disease is more likely to strike women who have endometriosis. Downloads Published Issue Section License Copyright (c) 2024 Pande Putu Firsta Widyaning This work is licensed under a Creative Commons Attribution 4.0 International License.

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Condition tags

endometriosis

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