EFFECT OF SURGICAL OPERATION FOR BENIGN OVARIAN TUMORS ON ANTI MULLERIAN HORMONE

Mohammed Aboul-Fotouh Abd El-Mageed, Mahmoud S. Zaki, Ahmed A. El-Tabaakh
In: Al-Azhar Medical Journal · 2021 · vol. 50(2) , pp. 963–974 · doi:10.21608/amj.2021.158443 · W3157677946
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⚙ AI-generated summary by claude@2026-06, 2026-06-12 ⓘ

This prospective cohort study found that surgical operations for benign ovarian tumors significantly decreased anti-Müllerian hormone levels post-operatively, with factors like age, lesion bilaterality, cyst size, surgery duration, and endometrioma type impacting this reduction.

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Abstract

Background: Surgical operation for benign ovarian tumors creates a potential risk for the ovarian reserve. Ovarian procedures including excision of cysts (cystectomy) are very commonly performed worldwide for various disorders. Objective: To study the long term effect of ovarian surgery on blood level of anti mullerian hormone. Patients and Methods: The present study was a prospective cohort study of patients who have benign ovarian tumor which carried on Patients from December 2019 to October 2020 at Obstetrics and Gynecology Department, Faculty of Medicine, Al-Azhar University. Results: There was a significant decrease in Anti mullerian hormone ( AMH ) post operatively by 25.79%. There was a significant relation between level of AMH and age of the patients. The old age had a low level of AMH. Also, the bilateral lesion showed a low level of AMH less than the unilateral lesions. The cyst size more than 5 cm showed a negative relation with level of AMH. The log duration of surgery had a negative effect on the level of AMH. The endometeriotic type showed a significant decrease in AMH level more than the other histopathological findings. Conclusion: Serum AMH levels could be preferred in determining the indication and selection of operative methods for benign gynecologic conditions, especially endometriomas.

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