Clear cell carcinoma developed on hepatic endometriosis: a case report and review of the literature

Caterina Chilà, É. Kermarrec, Kermarrec E, Edith Kermarrec, Valeria Loi, Loi V, Ilic J, Johanna Ilic, Zerbib E, Elie Zerbib, Ferrier C, Clément Ferrier, M Dahan, Dahan M, Meryl Dahan, Yohann Dabi, Dabi Y, Cyril Touboul, Touboul C, Emile Daraï, Daraï E
Journal of gynecology obstetrics and human reproduction · 2026 · vol. 55(7) , pp. 103200 · doi:10.1016/j.jogoh.2026.103200 · PMID:42067136 · W7159799049
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-09 ⓘ

This case report details a rare instance of clear cell carcinoma arising in a hepatic endometriosis lesion of a patient with a history of deep endometriosis and colorectal involvement.

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Abstract

Endometriosis is a chronic estrogen-dependent disorder that is generally localized in the pelvis affecting up to 10 % of women in the reproductive age. Extra-pelvic locations are estimated to 9 % of endometriosis women. However, the spread of the disease to parenchymal organs such as the liver is rare. Moreover, malignant transformation of hepatic endometriosis is exceptional. Here, we present a case of hepatic clear cell carcinoma developed on endometriosis lesion in a patient with prior surgery for deep endometriosis with colorectal involvement.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (34)

Source provenance

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