Does Helica treatment of early endometriosis confer short- and long-term benefits in terms of pain relief and sub-fertility?
Thirty-six patients with early endometriosis treated with Helica coagulation showed initial pain relief and conception rates, but these benefits declined within one year.
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This prospective observational study followed 36 women with laparoscopically confirmed stage 1–2 (early) endometriosis who had pelvic pain and/or sub-fertility and had received no endometriosis treatment for at least 6 months prior to Helica Thermal Coagulation. Pain relief was assessed at 6 weeks, 6 months, and 1 year, and pregnancy was confirmed by early ultrasound, with 31 patients included after exclusions for loss to follow-up and identification of alternative causes of pain. The study found high short-term pain improvement (93% pain free at 6 weeks) that declined over time (75% pain free/satisfied at 6 months and 37.5% at 1 year), alongside a cumulative pregnancy rate of 62% over 1 year, but with two early miscarriages. The authors explicitly note limitations including an observational design, small sample size, and the absence of larger randomized controlled trials to establish longer-term efficacy; the paper also reports no histological confirmation beyond laparoscopic visualization. This paper is centrally about endometriosis — it evaluates Helica Thermal Coagulation’s short- and long-term effects on pain relief and sub-fertility in early-stage endometriosis patients.
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