An unusual case of solid appendicular mass in a young female

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AI-generated summary by gemini-2.5-flash-lite, 2026-06-08

Endometriosis is a consideration for solid appendicular masses in women of childbearing age, though imaging findings are not definitive.

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AI-generated deep summary by claude@2026-06, 2026-06-16 · read from full text

The paper reports a 34-year-old woman evaluated for chronic constipation with intermittent rectal bleeding, in whom colonoscopy and CT identified a ~1.9–2 cm solid mass involving the base of the appendix and deforming the appendiceal orifice with indentation of the cecum. The initial working diagnosis was a solid appendiceal neoplasm, presumed to be a carcinoid tumor, and she underwent laparoscopic right hemicolectomy with tumor removal. Histopathology ultimately showed an endometrioma. The authors note a key caveat that endometriotic foci can be inaccessible to endoscopic biopsy due to focality, complicating preoperative differentiation between benign endometriosis-related disease and neoplasia. This paper is centrally about endometriosis — it describes an appendiceal endometrioma presenting as a mass mimicking an appendiceal tumor.

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Abstract

Endometriosis should be entertained as part of differential diagnosis in females in child-bearing age group when there is an incidental finding of solid neoplasm on imaging. It helps to guide physicians for appropriate management. It is important to emphasize that no radiological or imaging finding is pathognomonic for endometriosis.
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Question

A 34-year-old female was evaluated for chronic constipation with intermittent rectal bleeding. Colonoscopy revealed a deformed appendicular orifice with a mass causing indentation of the cecum ( Figure 1 ). Computerized tomography (CT) of abdomen showed solid mass close to 2 cm involving the base of appendix ( Figure 2 ). How to best intervene? Colonoscopy showing the mass causing indentation of the cecum. CT abdomen showing appendix in midline with a filling defect at its base (green arrow) and a 1.9 cm appendicular solid mass (purple arrow).

Conflicts

None declared.

Discussion

The initial diagnosis was a solid neoplasm of appendix, presumably carcinoid tumor. Considering the size and tumor bulging into cecum, patient underwent laparoscopic right hemicolectomy with tumor removal. Histopathology showed endometrioma. Endometriosis can affect various parts of gastrointestinal system from small intestine to anus. It can present as acute appendicitis, invagination, colic, melena, or asymptomatic 1 . Often Endometriotic foci were inaccessible to endoscopic biopsy due to the focality as in this case. As the surgical management varies widely from simple appendectomy to right hemicolectomy, there is a need to devise an evaluation method to better differentiate benign versus neoplastic disease preoperatively.

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Condition tags

endometriosis

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europepmc
last seen: 2026-09-03T06:15:13.668130+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:17:46.044120+00:00
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