The value of DWI and IVIM for predicting the outcome of adenomyosis-associated infertile patients before transferring frozen-thawed embryos

The study evaluated whether intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) parameters measured before frozen-thawed embryo transfer could predict pregnancy outcomes in 19 adenomyosis-associated infertile patients who received GnRH-a pretreatment. Using IVIM-DWI, the authors calculated ADC-related metrics for adenomyosis, including ADC, D, D*, and f, and compared these between pregnancy and non-pregnancy groups. They found that ADC was significantly higher in the pregnancy group than the non-pregnancy group (p = 0.021), while other diffusion-related parameters did not show significant differences. The study is limited by its small sample size and provides only preliminary evidence needing further study. This paper is centrally about adenomyosis — it tests whether IVIM/DWI imaging before frozen-thawed embryo transfer can predict pregnancy outcomes in adenomyosis-associated infertile patients after GnRH-a pretreatment.

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