Ovarian hemorrhage complicating warfarin sodium anticoagulant therapy

S Matseoane, Stephen Matseoane, J A Batts, James A. Batts, Edgar O. Mandeville, E O Mandeville
American journal of obstetrics and gynecology · 1976 · vol. 124(7) , pp. 766–767 · doi:10.1016/s0002-9378(16)33352-x · PMID:1258938 · W2469525594
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Three reproductive-age women on warfarin therapy for pulmonary embolism experienced ovarian cyst rupture and intraperitoneal hemorrhage requiring surgery, highlighting the need to consider anticoagulant complications in patients with abdominal pain.

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Abstract

Three cases of women in the reproductive age group who received warfarin sodium therapy for pulmonary embolism are presented. The therapy was complicated by rupture of ovarian cysts with intraperitoneal hemorrhage necessitating exploratory laparatomy. The possibility of intraperitoneal hemorrhage must be considered in patients who present with abdominal pain and a history of anticoagulant therapy. Lack of awareness of the complication may result in delay in making a correct diagnosis and instituting appropriate therapy.

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MeSH descriptors

Ovarian Diseases Warfarin Adult Female Humans Ovarian Cysts Ovarian Cysts Ovarian Diseases Pulmonary Embolism Pulmonary Embolism Rupture, Spontaneous Warfarin Warfarin

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