Fertility sparing treatment in an infertile patient with severe adenomyosis and a uterine fibroid: a case report

Swapna Yaramareddy, Siyonu Kumari Sardena, Nom Kumar Naik Bhukya, Tulasi Ram Naik Menavath
In: International Journal of Reproduction, Contraception, Obstetrics and Gynecology · 2023 · vol. 12(5) , pp. 1510–1512 · doi:10.18203/2320-1770.ijrcog20231254 · W4367369337
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This case report describes a nulliparous woman with severe adenomyosis and uterine fibroids who achieved pregnancy through in vitro fertilization and a downregulated frozen embryo transfer.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 ⓘ

This case report describes a 33-year-old nulliparous woman with primary infertility for 18 years who was diagnosed with severe adenomyosis and uterine fibroids. Fertility-sparing management with in vitro fertilization followed by a properly downregulated frozen embryo transfer resulted in a successful conception. The authors frame downregulated FET planning as the treatment of choice to align with fertility preservation goals. As a single-patient report, it provides limited generalizability beyond this individual case. This paper is centrally about endometriosis—reframing adenomyosis and uterine fibroids in an IVF downregulated FET fertility-sparing context.

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Abstract

Adenomyosis and uterine leiomyoma are benign lesions of the myometrium. Adenomyosis is a myometrial lesion characterised by the presence of ectopic endometrium with or without hyperplasia of the surrounding myometrium. Uterine fibroids, also called leiomyomas or myomas, are benign tumours that arise from the smooth muscle of the uterus. A 33-year-old nulliparous woman attended the clinic with primary infertility for 18 years. She was diagnosed with severe adenomyosis and uterine fibroids. She conceived successfully after undergoing in vitro fertilization (IVF) and a downregulated frozen embryo transfer (FET). Adenomyosis is a common cause of primary and secondary dysmenorrhea associated with infertility in young, nulliparous women. Fertility preservation is the primary goal in this population. Medical management is essential, and a properly downregulated and planned FET is the treatment of choice.

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Condition tags

adenomyosisdysmenorrheainfertility

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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