Exacerbation of adenomyosis symptomatology by estrogen-progestin therapy: a case report and histopathological observations

R J Falk, B R Mullin
International journal of fertility · 1989 · doi:10.1186/1752-153x-6-109 · PMID:2574708
case-report OA: gold CC-BY-4.0
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Abstract

The present case report illustrates the hormonal sensitivity of adenomyosis. Administration of an estrogen-progestin combination for what was felt to be symptomatic endometriosis resulted in exacerbation of symptoms and growth of adenomyomas. Histopathologic examination of the hysterectomy specimen revealed a pattern of decidualization previously unreported, but consistent with current theories of experimental in vivo and in vitro decidua formation.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Contraceptives, Oral, Combined Contraceptives, Oral, Combined Endometriosis Ethynodiol Diacetate Leiomyoma Mestranol Neoplasms, Multiple Primary Uterine Neoplasms Adult Endometriosis Endometriosis Ethynodiol Diacetate Female Humans Leiomyoma Leiomyoma Mestranol Neoplasms, Multiple Primary Neoplasms, Multiple Primary Uterine Neoplasms

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europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
pubmed
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License: CC-BY-4.0 · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine