Night sweats and elevated follicle-stimulating hormone levels while taking selective serotonin reuptake inhibitors

Lora K. Shahine, Ruth B. Lathi
Obstetrics & Gynecology · 2006 · vol. 108(3) , pp. 741–742 · doi:10.1097/01.aog.0000189718.07777.c1 · PMID:17018486 · W2069951694
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-09 ⓘ

This case report observed night sweats and elevated follicle-stimulating hormone in a reproductive-aged woman taking SSRIs for depression.

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This case report describes a reproductive-aged woman undergoing infertility treatment who developed night sweats and elevated follicle-stimulating hormone levels while taking selective serotonin reuptake inhibitors for depression. The authors note that while SSRIs are known to cause vasomotor symptoms, their specific impact on gonadotropin levels and normal reproductive function in women of childbearing age remains unclear. The paper highlights the need for further research into how these antidepressants might interfere with hormonal balance and fertility outcomes. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed to women with depression and anxiety disorders. Although night sweats are a reported adverse effect, some women have relief of vasomotor symptoms during perimenopausal period while taking them. The relationships between SSRIs, thermoregulation, gonadotropins, and estrogen and their connection to fertility remain unclear. CASE: A reproductive-aged woman, seeking treatment for infertility, experienced night sweats and elevated follicle-stimulating hormone levels while taking SSRIs for treatment of depression. CONCLUSION: Many women of reproductive age are taking SSRIs, but the affect of SSRIs on normal reproductive function is unknown and further research in this area is needed.
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Background

Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed to women with depression and anxiety disorders. Although night sweats are a reported adverse effect, some women have relief of vasomotor symptoms during perimenopausal period while taking them. The relationships between SSRIs, thermoregulation, gonadotropins, and estrogen and their connection to fertility remain unclear. CASE: A reproductive-aged woman, seeking treatment for infertility, experienced night sweats and elevated follicle-stimulating hormone levels while taking SSRIs for treatment of depression.

Conclusion

Many women of reproductive age are taking SSRIs, but the affect of SSRIs on normal reproductive function is unknown and further research in this area is needed. A reproductive-aged woman, seeking treatment for infertility, experienced night sweats and elevated follicle-stimulating hormone levels while taking 2 different selective serotonin reuptake inhibitors. Copyright © 2006 by The American College of Obstetricians and Gynecologists.

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Condition tags

infertility

MeSH descriptors

Depression Follicle Stimulating Hormone Selective Serotonin Reuptake Inhibitors Sweating Adult Depression Female Fluoxetine Fluoxetine Follicle Stimulating Hormone Humans Infertility, Female Infertility, Female Infertility, Female Paroxetine Paroxetine Selective Serotonin Reuptake Inhibitors Sweating

Citation neighborhood (sparse)

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Cites (1)

References (14)

Source provenance

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