In vitro Fertilization Applied for Tubal and Non‐Tubal Causes of Infertility

John L. Yovich, Jeanne M. Yovich, Ann I. Tuvik, S. M. Junk, Barbara Bootsma, Phillip Matson
In: Asia-Oceania Journal of Obstetrics and Gynaecology · 1986 · vol. 12(4) , pp. 483–488 · doi:10.1111/j.1447-0756.1986.tb00222.x · PMID:3827727 · W1963886108
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Abstract

Abstract A combined service and research program of IVF‐ET was established at PIVET Laboratory, Perth, Western Australia in 1981. By May 1985, 592 couples have had a mean of 1.66 treatment cycles with a total of 140 pregnancies achieved (23.7% per couple). The earliest cases were treated for occlusive tubal disease, but increasingly, a wide range of infertility disorders have been managed by IVF‐ET. The pregnancy rate achieved for tubal disease was 23.3%. Rates are significantly lower in women with endometriosis (9.1%; p<0.01) and significantly higher where the woman has no recognizable factor (including those treated for failed artificial insemination by donor semen) and those with circulating antispermatozoal antibodies (up to 47.6%; p<0.001). With regard to male factors, applying the treatment methods described, pregnancy rates did not vary between groups (mean 23.7%) although donor semen was used where an insufficient number of motile spermatozoa was obtained from husband's semen.

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endometriosisinfertility

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