Recombinant hCG versus Dual Triggering for final oocyte maturation in ICSI Cycles among Poor Responders with Endometriosis

Women with endometriosis often face difficulty becoming pregnant, mainly when their ovaries produce only a small number of eggs. In assisted fertility treatments, hormones are used to help eggs mature before they are collected. One common method uses a hormone called hCG, while another approach, known as dual triggering, combines hCG with an additional hormone to better mimic the body's natural process. In this study, we compared these two methods in 152 women with endometriosis and poor ovarian response undergoing fertility treatment. We found that women who received the two-hormone method produced more fully mature eggs, more good-quality embryos, and had higher chances of pregnancy than those who received hCG alone. These findings suggest that using both hormones may offer a better chance of success for some women with endometriosis undergoing fertility treatment and could help doctors tailor treatment to individual patient needs.